Lupinus angustifolius

Peterson, D., Ellis, Z., Harris, D. and Spadek, Z. (1987). Acute toxicity of the major alkaloids of cultivated Lupinus angustifolius seeds to rats. J. Appl. Toxicol. 7 51-53. 

Gulewicz, P., Szymaniec, S., Bubak, B., Frias, J., Vidal-Valverde, C., Trojanowska, K. and Gulewicz, K. 2002. Biological activity of a-galactoside preparations from Lupinus angustifolius L. and Pisum sativum L. seeds. Journal of Agriculture and Food Chemistry, 50 384-389. 

Wysocka, W. and Przybyl, A. 1994. Alkaloids from Lupinus albus and Lupinus angustifolius L. an efficient method of extraction. Science of Legumes, 1 37-50. 

Hirai, M. Y., Suzuki, H., Yamazaki, M. and Saito, K. 2000. Biochemical andpatrial molecular characterization of bitter and sweet form of Lupinus angustifolius, an experimental model for study of molecular regulation of quinolizidine alkaloids biosynthesis. Chemistry and Pharmacy. Bulletin, 48 1458-1461. 

Aniszewski, T., Drozdov, S. N., Kholoptseva, E. S., Kurets, V. K., Obshatko, L. A., Popov, E. G. and Talanov, A. V. 2001. Effects of light and temperature parameters on net photosynthetic carbondioxide fixation by whole plants of five lupin species Lupinus albus L., Lupinus angustifolius L., Lupinus luteus L., Lupinus mutabilis Sweet, and Lupinus polyphyllus Lindl.). Acta Agriculturae Scandinavica, 51 17-27. 

Rubio, L.A., Brenes, A. and Centeno, C. (2003) Effects of feeding growing broiler chickens with practical diets containing sweet lupin (Lupinus angustifolius) seed meal. British Poultry Science 44, 391-397. 

Table 4.1.17A. Lupinseed meal sweet white (IFN 5-27-717). The ground whole seed of the species Lupinus albus, Lupinus angustifolius or Lupinus luteus. It has to contain less than 0.3g total alkaloids/kg. The species of seed must be listed after the name Sweet lupin seeds, ground . (From CFIA, 2007.) ...

Tyski, S., Markiewicz, M., Gulewicz, K. and Twardowski, T. 1988. The effect of lupin alkaloids and ethanol extracts from seeds of Lupinus angustifolius on selected bacterial strains. J. Plant Physiol. 133, 240-242... 

Angustifoline, C14H22ON2 (mp 81° [ ]i —8.0°), has been isolated from Lupinus angustifolius L., L. polyphyllus L., and L. albus L. Its structure was elucidated almost simultaneously by three different groups (31-33). It forms an A-acetyl derivative, has a terminal double bond as indicated by IR-spectra and proved by oxidation to formaldehyde, and reduction of the lactam grouping with lithium aluminum hydride generates a tmws-quinolizidine system (trans bands in the IR-spectrum), and these facts lead to structure XXXVII for angustifoline. 

Figure 1.2. Distribution of organisms with distance from the roots of 18-day-old lupin (Lupinus angustifolius L.). (From Rovira and Davey, 1974.)...

Romer. W.. Kang Dong Kyu, Egle, K., Gerke, J. and Keller, H. (2000). The acquisition of cadmium by Lupinus albus L., Lupinus angustifolius L., and Lolium multiflorum Lam. J. Plant Nutr. Soil Sci. 163, 623-628. 

A compound isolated from old extracts of Lupinus angustifolius seeds was shown previously to be an artefact derived from reaction of angustifoline (10) and hydroxymethylfurfural. The remaining structural features of the compound (11), including its absolute configuration, have now been established by X-ray analysis. 

The O-acetyl-conjugates were encountered only infrequently in plants, they were detected as O-acetyl-ZRMP and O-acetyl-DHZRMP in Lupinus angustifolius after... 

Dilworth MJ and Bisseling T (1984) Cobalt and nitrogen fixation in Lupinus angustifolius L. III. 

Riley IT and Dilworth MJ (1985 b) Recovery of cobalt d cient nodules in Lupinus angustifolius L. New Phytol 100 361-365. 

Thermopsine (133) appeared after rhombifoline (134). As in the biosynthesis of the alkaloids of Lupinus angustifolius, no evidence could be found for the formation of sparteine. Finally, two unknown alkaloids, it was noted, were labelled early in both Thermopsis species. 

Ten alkaloids have now been isolated from the branches of Genista cinerea DC. These include six esters of 13-hydroxylupanine, four of which have been previously reported. The two esters recently isolated (from Provengal plants) are cinevanine (10), which is the vanillic acid ester of 13-hydroxylupanine, and 13 benzoyloxylupanine. The former had not previously been isolated from natural sources, but the latter had been found previously in Lupinus angustifolius and L albus. The four remaining alkaloids of Genista cinerea are 13-hydroxylupanine, lupanine, anagyrine, and hystrine (11), a base which was first obtained from G. hystrix Lange. 

Blagrove RJ, Gillespie JM (1975). Isolation, purification and characterization of the seed globuUns of lupinus angustifolius. Aust. J. Plant Physiol, 2 13-27. 

Butler WH, Ford GP, Creasy DM (1996). A 90-day feeding study of lupin Lupinus angustifolius) flour spiked with lupin alkaloids in the rat. Food. Chem. Toxicol, 34 531-536. 

Lilley GG (1986). The subunit structure and stability of conglutin delta, a sulphur-rich protein from the seeds of Lupinus angustifolius L. J. Set FoodAgric., 37 895-907. 

Martins JM, Riottot M, de Abreu MC, et al. (2005). Cholesterol-lowering effects of dietary blue lupin (Lupinus angustifolius L.) in intact and ileorectal anastomosed pigs. J. Lipid Res., 46 1539-1547. 

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