Liposome comparison

Matthay, K.K., Heath, T.D., Badger, C.C., Bernstein, I.D., and Papahadjopoulos, D. (1986) Antibody-directed liposomes Comparison of various ligands for association, endocytosis and drug delivery. Cancer Res. 46, 4904. 

Matthay KK, Heath TD, Badger CC, Bernstein ID, Papahadjopoulos D. Antibody-directed liposomes comparison of various ligands for association, endo-cytosis, and drug delivery. Cancer Res 1986 46(10) 4904 910. 

Legendre, J.Y. and Szoka, F.C. (1992) Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes-comparison with cationic liposomes. Pharm. Res., 9, 1235-1242. 

Gregoriades G, Panagiotidi C (1989) Immunoadjuvant action of liposomes Comparison with other adjuvants. Immimol Lett 20 237-240... 

In comparison to intravenous administration of MLV, which usually results in a rapid and almost quantitative uptake into liver and spleen, the fraction taken up into these organs is lower after intraperitoneal injection of these large liposomes. The reason might be that liposomes are trapped in lymph nodes and degradation of the liposomes in the peritoneal cavity can occur (Ellens et al., 1981 Parker et al., 1982) besides, several types of liposomes are degraded more quickly in lymphatic fluid than in plasma (Parker et al, 1981a,b). 

Grliner, S. M., Lenk, R. P., Janoff, A. S., and Ostro, M. J. (1985). Novel multilayered lipid vesicles Comparison of physical characteristics of multilamellar liposomes and stable plurilamellar vesicles, Biochemistry. 24. 2833-2842. 

Altered tissue distribution of amphotericin B by liposomal encapsulation Comparison of normal mice and mice infected with Candida albicans. Cancer Drug Deliv., 1, 199-205. 

Parker, R. J., Priester, E. R., and Sieber, S. M. (1982). Comparison of lymphatic uptake metabolism, excretion, and biodistribution of free and liposome-entrapped (l cjcytosine beta-D-arabinofuranoside following intraperitoneal administration in rats, Drug. Me tab. Dispos., 10, 40-46. 

Peeters, P. A. M., Brunink, B. G., Eling, W. M. C., and Crommelin, D. J. A. (1989). Therapeutic effect of chloroquirie (CQ) containing immunoliposomes in rats infected with Plasmodium berghei parasitized mouse red blood cells comparison with combinations of antibodies and CQ or liposomal CQ, Biochim. Biophys Acta, 981, 269-276. 

Figure 5.7 Comparison of liposome-water (solid lines) to octanol-water (dashed lines) lipophilicity profiles for a weak acid, a weak base, and an ampholyte. [Avdeef, A., Curr. Topics Med. Chem., 1, 277-351 (2001). Reproduced with permission from Bentham Science Publishers, Ltd.]...

Ottiger, C. Wunderli-Allenspach, H., Immobilized artificial membrane (IAM)-HPLC for partition studies of neutral and ionized acids and bases in comparison with the liposomal partition system, Pharm. Res. 16, 643-650 (1999). 

Cantrell et al. (2003) studied the quenching of 02 by several dietary carotenoids in dipalmitoyl phosphatidylcholine (DPPC) unilamellar liposomes. These workers used water soluble and lipid soluble 02 sensitizers so that a comparison of the efficiencies of quenching 02 generated within and outside the membrane model could be made. Perhaps surprisingly there was little difference in the efficiency of quenching in either situation. Typical results are presented in Table 14.3 (taken from Cantrell et al. (2003 and 2006)). 

For comparison, included in Table 14.3 are the kq values obtained in detergent micelles along with kq values obtained in homogeneous solvent benzene. As can be seen, the second-order rate constant for 02 quenching in a liposomal environment is a factor of 4 lower for (3-CAR compared to the second-order rate constant obtained in the aromatic solvent. While, there is a marked 80-130 fold difference between the kq values determined in liposomal environments compared to the kq values determined in the aromatic solvent for the XANs. 

ESCHER, B. I., SCHWARZENBACH, R. P., Westall, J. C., Evaluation of liposome-water partitioning of organic acids and bases. 2. Comparison of experimental determination methods, Environ. Sci. Technol. 2000, 34, 3962-3968. 

Amongst the synthetic magnesium(II) complexes, a comparison of bis(pyridine)magnesium(II)-tetrabenzoporphyrin (26) with bis(pyridine)magnesium(II)-octamethyltetrabenzoporphyrin (10) in vitro (HeLa cells), and in vivo using liposomal delivery, showed that while (26) was more effective than (10) in cell kill, (10) had the greater tumor selectivity ([tumor]/[muscle] = 36.0 after 24 h). Zinc(II) tetrabenzoporphyrin also showed promising activity nickel(II) tetrabenzoporphyrin derivatives were inactive.117... 

Shek, P.N., and Sabiston, B.H. (1982b) Immune response mediated by liposome-associated protein antigens. II. Comparison of the effectiveness of vesicle-entrapped and surface-associated antigens in immu-nopotentiation. Immunology 47, 627. 

Shek, P.N., B.Y.K. Yung, N.Z. Stanacev, Comparison between Multilamellar and Unilamellar Liposomes in Enhancing Antibody Formation, Immunology. 49, 37,1983. 

Fattale, E. Rojas, J. Roblot-Treupal, L. Andremont, A., Couveur, P. Ampicillin-loaded liposomes and nanoparticles Comparison of drug loading, drug release and in vitro antimicrobial activity. J. Microcapsulation 8 (I), p. 29-36, 1991... 

Beyer, U., Rothen-Rutishauser, B., Unger, C., Wunderli-Allenspach, H., Kratz, F., Differences in the intracellular distribution of acid-sensitive doxorubicin-protein conjugates in comparison to free and liposomal formulated doxorubicin as shown by confocal microscopy. Pharm Res 18, 29-38 (2001). 

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