Life-span development

The in vivo carcinogenic activities of Trp-P-1, Trp-P-2, Glu-P-1, Glu-P-2, AaC, and MeAaC were detected in CDFi mice by feeding. Mice which were fed a diet containing 0.02% Trp-P-1 or Trp-P-2 for an entire life span developed specifically hepatocellular carcinomas females were more susceptible than males (37) (Table V). Female rats but not males fed a diet containing 0.01% Trp-P-2 developed hemangioendothelial sarcoma and neoplastic nodules of the liver (38). 

While the effective life of Norplant I is at least five years, most of the users have the implants removed at an earlier time. Norplant II was developed to have a shorter life-span, and is composed of only two rods. Levonorgestrel is dispersed in the silastic matrix which is then inserted into a thin silastic tubing. This product has an effective life-span of two to three years (36). Because it is composed of only two rods, Norplant II also is easier to implant and remove. 

Ecological planning in this context will help to avoid ecological disasters (e.g. excessive weed growth in stored water) and maximize the life span of the benefits derived from the development. It will be clear that this holistic approach to development has economic as well as ecological advantages. 

Developmental Toxicity—The occurrence of adverse effects on the developing organism that may result from exposure to a chemical prior to conception (either parent), during prenatal development, or postnatally to the time of sexual maturation. Adverse developmental effects may be detected at any point in the life span of the organism. 

Fluorescent light fixtures vary in quality. Lower priced ones often develop an annoying hum after being in operation for a time, and the transformers may have a limited life span. High quality fixtures are more expensive but are a good investment. 

Significant strides have been made in past decades with development of new therapies that have led to the ever-lengthening CF life-span. Since the discovery of the CF gene and the CFTR protein defect, research has focused on gene therapy as a way to restore normal CFTR function through DNA transfer. 

Terranova, P. 1997. Potential roles of tumor necrosis factor-alpha in follicular development, ovulation and the life-span of the corpus luteum. Domestic Animal Endocrinology 14(1), 1-15. 

Beagles, prenatal and early neonatal stages, given single acute dose of 0.2-1.0 Gy, then observed over 11-year life span Irradiation at all ages was associated with increased risk of decreased fertility inhibited growth and development lower brain weight and increase in fatal neoplasms 5... 

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