Life cycle assessment history

Description of process/environment Quality-related critical parameters Purpose and objectives of the system Major benefits of the system Special requirements Specific training needs System operating strategy Related GMP compliance/regulations Physical and logical boundaries System GMP risk assessment System validation rationale Life-cycle documentation Assumptions and prerequisites Limitations and exclusions Quality-related critical parameters/data Standard operating procedures System requirement specification Supplier and system history... 

Many of the models simulate the population dynamics of the species often used in ecotoxicological laboratory studies. Often these species are highly relevant for risk assessments, but they are also characterized by life cycles that make them suitable for laboratory culture. Therefore, regulators are sometimes more concerned about other species that are perceived to have life histories that make them more vulnerable or which are thought to be more important for ecosystem functioning. 

The sophistication of chemosensory assessment of predation risk seems remarkable. Even at the embryonic level we see the complexity and specificity of the chemical cues used in this assessment. Two patterns have emerged from the studies conducted to date however, more studies are needed to verify these patterns. We also need to branch out and examine how life-history shifts at one point in the life-cycle influences the rest of the life cycle. Moreover, we need to consider the natural level of predation risk in each system we study because the selection pressures may differ from one population to the next. By examining each system more closely we start to understand how predation shapes population and community structure. 

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