Laurencia majuscula

Itoh, T., Matsuo, Y. and Suzuki, M. 1997b. Sesquiterpenoids of Laurencia majuscula... 

Suzuki, M. and Kurosawa, E. 1978. Two new halogenated sesquiterpenes from the red alga Laurencia majuscula. Tetrahedron Lett. 4805-4808. 

Kurosawa, E. and Kurata, K. 1987. Majusculone, a novel norchamigrane-type metabolite from the red alga Laurencia majuscula Harvey. Buh. Chem. Soc. Japan 60 3795-3796. 

The new red algal species Laurencia mariannensis from the Great Barrier Reef provides the novel sesquiterpene 297, along with the known pacifenol and deoxy-prepacifenol, which are now fully characterized by NMR for the first time (539). The Philippine Laurencia majuscula has furnished 13 novel halogenated sesquiterpenes 298-310, of which the major components are the majapolenes A (298, 299) (two diastereomers), which are also found in Laurencia caraibica (540). Most of these compounds occur as inseparable diastereomers. A collection of Laurencia majuscula from the South China Sea has yielded the cedrene-type sesquiterpene majusin (311) (541). A new sesquiterpene dichloroimine, stylotellane A (312), was isolated from the sponge Stylotella aurantium (Fig. 3.3) (542). 

Whereas Okinawan Laurencia cartilaginea and Laurencia concreta yielded no halogenated metabolites, Laurencia majuscula from these waters afforded (6/ ,9/ ,105)-10-bromo-9-hydroxychamigra-2,7(14)-diene (361) (577), which... 

Erickson KL, Beutler JA, Gray GN, Cardellina II JH, Boyd MR (1995) Majapolene A, a Cytotoxic Peroxide, and Related Sesquiterpenes from the Red Alga Laurencia majuscula. J Nat Prod 58 1848... 

Xu X-H, Zeng L-M, Su J-Y (1997) Tricyclic Sesquiterpene from Laurencia majuscula. Chem Res Chin Univer 13 176... 

Vairappan CS (2003) Potent Antibacterial Activity of Halogenated Metabolites from Malaysian Red Algae, Laurencia majuscula (Rhodomelaceae, Ceramiales). Biomol Engi-ner 20 255... 

Sheldrake HM, Jamieson C, Burton JW (2006) The Changing Faces of Halogenated Marine Natural Products. Total Synthesis of the Reported Structures of Elatenyne and an Enyne from Laurencia majuscula. Angew Chem Int Ed 45 7199... 

Xu X-H, Zhu Y-D, Gao W, Kong C-H (2006) Agricultural lead compounds from Laurencia majuscula. In Proceedings of international forum on green chemical science engineering and process systems engineering, Tianjin, vol 1, pp 538-541... 

The cytotoxic activity of sesquiterpene lactones in species Ajania przewalskii Poljakov and Ligularia platyglossa was also reported [143, 144]. The volatile principles of Citrus aurantifolia inhibit proliferation inhibition of human colon cancer cells by apoptosis. The volatile sesquiterpenes showed DNA fragmentatiOTi and induction of caspase-3 [145]. The antiproUferative and anticancer activity of Nigella sativa was established [146]. Sesquiterpene lactmie from Schistochila glaucescens, Laurencia majuscula, Curcuma parviflora, and Liverwort shows... 

Recently, a novel carbon skeleton derived from cha-migrane has been characterized in gomerones A-C, three chlorinated cydohexenones isolated from the Spanish species Laurencia majuscula collected at La Gomera, Canary Islands (Diaz-Marrero et al., 2008). 

Diaz-Marrero, A.R., Brito, I., de la Rosa, J.M., Darias, J., and Cueto, M. (2008) Gomerones A-C, halogenated sesquiterpenoids with a novel carbon skeleton from Laurencia majuscula. Tetrahedron, 64, 10821-10824. 

Sheldrake, H.M., Jamieson, C., and Button, J.W. (2006) The changing face of halogenated marine natural products total synthesis of the reported structures of elatenyne and an enyne from Laurencia majuscula. Angew. Chem. Int. Ed., 45, 7199-7202. 

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