Lactose powders

Potassium chlorate, Sulfur, Zinc powder, Sodium bicarbonate Zinc powder, Zinc oxide, Hexachoroethane Potassium chlorate, Paranitranihne, Lactose, Powdered sugar Potassium chlorate, Aniline, Napthalene azodimethyl Potassium chlorate, Napthalene, Azodimethyl aniline, Auramine, Sodium bicarbonate, Sulfur... 

Potassium chlorate, ParanitranUine, Lactose, Powdered sugar... 

Problems arising from the crystallization of lactose in milk and whey powders may also be avoided or controlled by pre-crystallizing the lactose. Essentially, this involves adding finely divided lactose powder which acts as nuclei on which the supersaturated lactose crystallizes. Addition of 0.5 kg of finely ground lactose to the amount of concentrated product (whole milk, skim milk or whey) containing 1 tonne of lactose will induce the formation of c. 106 crystals ml-1, about 95% of which will have dimensions less than 10/an and 100% less than 15 /an, i.e. too small to cause textural defects. 

Ethanol and methanol (preferred with less than 3% moisture) have been used to extract lactose from skim milk or whey powders (Kyle and Henderson 1970). The dried lactose powder that crystallized from the alcoholic extract was believed to be anhydrous a-lactose, but other work indicates that the product is a mixture of anhydrous a- and /3-lactose (Lim and Nickerson 1973). 

The pharmaceutical industry has been using lactose for many years because its properties that aid flow characteristics and tablet or pill formation. The drug is distributed uniformly in lactose powder, which is easily molded or compressed into tablets. These have good dispers-... 

Of the 96 patients selected, 55 were positive for Dermatophagoides (57%) and 41 were positive for Graminaceae or Parietaria (43%). The patients selected were randomized into two groups the active group that received specific LNIT and the placebo group that received a lactose powder formulation in order to be taste-masked. Ah patients gave written informed consent. 

Milk and milk products raw milks (as defined in Article 2 of Directive 92/46/EEC), milk powder, skimmed milk, skimmed milk powder, buttermilk, buttermilk powder, whey, whey powder, whey powder low in sugar, whey protein powder (extracted by physical treatment), casein powder and lactose powder... 

Fig. 6 Families of yield loci for lactose powder coated with 0.5 X 10 mol of light paraffin at 20 C. Pf A., 0.346 x, 0.282 , 0.279 o, 0.261 (A) normal stress (B) compound stress. (From Reft .)...

Hickey, A.J. Concession, N.M. Chaos in rotating lactose powder beds. Part. Sci. Tech. 1996, 14, 15-25. 

Lo Y-I. Tsai J-C. Kuo J-H. Liposomes and disaccharides as carriers in spray-dried powder-formulations of superoxide dismutase J Control Release 2004 94 259-72. Lcchuga-Ballcstcros D, Charan C, Stults CLM. etal. Triteucine improves aerosol performance and stability of spray-dried powders for inhalation. J Pharm Sci 2007 96(5) 1258-69. Faldt P, Bergenstiihl B. The surface composition of spray-dried protein-lactose powders, niysiochcm Eng Aspects 1993 183-90. 

FIG. 21-106 Agglomerate formation vs. spray flux. Lactose powder with water and HPLC solutions. [Ajier Hop-good (loc. cit.).]... 

Bronlund, J. and Paterson, T. Moisture sorption isotherms for crystalline, amorphous and predominantly crystalline lactose powders, Int. Dairy /., 14, 247, 2004. 

M. Angberg, C. Nystrom, and S. Castensson, Evaluation of heat-conduction microcalorimetry in pharmaceutical stability studies. III. Crystallographic changes due to water vapor uptake in anhydrous lactose powder, lnt. J. Pharm. 73, 209-220(1991). 

Fig. 2 Median cough frequency (per 10 min) for patients with cough associated with common cold. Immediately after the baseline measurement (0 min) patients were treated with either a single dose of 30 mg dextromethorphan powder in a hard gelatin capsule round symbols, n = 21) or a matched placebo capsule containing lactose powder square symbols, n = 22). (Lee et al. 2000)...

Faldt, P. and Bergenstahl, B., The surface composition of spray-dried protein-lactose powders. Colloid Surf. A, 90, 183-90 (1994). 

Infrared spectroscopy has been extensively used in both qualitative and quantitative pharmaceutical analysis [1-3], This technique is important for the evaluation of the raw materials used in production, the active ingredients and the excipients (the inert ingredients in a drug formulation, e.g. lactose powder, hydroxypropyl cellulose capsules, etc.). Although nuclear magnetic resonance spectroscopy and mass spectrometry are widely used in the pharmaceutical industry for the identification of drug substances, infrared spectroscopy can provide valuable additional structural information, such as the presence of certain functional groups. 

Schaafsma et al. (1999) Lactose powder with water and 3-8% PVP solution binders Packed bed in petri dish Drop size... 

Crooks and Schade (1978) 5% Phenylbutazone in lactose powder mix with 10% solution Eluid bed Binder addition rate... 

Kristensen and Schaefer (1994) Lactose powder with PEG300 and PEG6000 High shear Viscosity, binder dispersion, shear forces... 

During the storage of amorphous lactose powder, no crystallization is observed for Ow < 0.35. Above 0.35, the glass transition temperature Tg decreases to values below the ambient temperature, leading to crystallization at a rate depending on... 

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