Laboratory report preparation conclusions

The DQAR may be part of a general report that details all project activities, findings, and conclusions, or be a separate document that becomes part of the permanent project record. Typically, the chemist who conducts DQA prepares the DQAR. The information needed for the DQAR preparation comprises field records, laboratory data, data evaluation summaries, sample data tabulated according to their use, and results of statistical testing. 

In conclusion, some of the high salt rejection properties found with interfacial polypiperazineamide membranes in the laboratory could not be attained by a machine-made membrane. However, the machine-formed membrane may still find applications where high rejection of monovalent salts is not required but where high flux and rejection of larger solutes are useful. A limited effort to replace piperazine in the reaction with piperazine-terminated oligomers did not appear to resolve the membrane reproducability problem. Recent studies made on the use of piperazine terminated oligomers in composite membrane preparation were reported by R. Sudak et al at Membrane Systems, Inc. (46) and by J.F. Wolfe et al at Stanford Research Institute (47). 

The experimental results which lead to these conclusions are summarized In Table I. Elemental analyses, conducted by a commercial laboratory, are presented In the form of a ratio of the relative numbers of atoms of C, H, N, and 0 normalized to 3 carbon atoms per monomer unit. IR spectra were obtained In-house using a Perkin Elmer 298 IR spectrophotometer. Solid probe magic angle spinning NMR experiments were performed at the National Bureau of Standards. All of these analyses were performed on bulk (l.e. pyrolyzed In batches of lg) samples of 485,000 average molecular weight ultrapure PAN prepared In a tube furnace evacuated by a mechanical vacuum pump, and are reported on In detail elsewhere.(13) Table I also summarizes electrical conductivity and optical absorption experimental results obtained using thin films of PAN solution cast In dlmethylformamlde. 

In contrast to the preceding observations and conclusions, there are reports from one laboratory that the mechanism of peptide formation resembles that of protein synthesis. Cellfree preparations of B. hrevis were observed to synthesize gramicidin and tyrocidine provided that both a 140,000 X g supernatant solution and a ribosomal preparation are present (in addition to Mg+, ATP, phosphoenol-pyruvic acid, pyruvic kinase, glutathione, and amino acid mixture). The supernatant solution presumably supplies s-RNA and amino acid activating enzymes. In this system, peptide synthesis is suppressed by exposure of either the supernatant or ribosomal portions to RNase (Uemura et al., 1963)- Furthermore, neither chloramphenicol nor puromycin are capable of differentiating protein from peptide synthesis in this system the formation of each of the products is inhibited 98% by either 10 (xg/ml of the former or 100 fi.g/ml of the latter antibiotic (Okuda et al., 1964b). 

---