Naphthalene, l-

Amino-3-hydroxy-7-nitro-l-naphthalene-sulfonic acid [6259-63-8]... 

CiftHijNOjS 42399-49-5) see Diltiazem (4S)-3,4-dihydro-4-hydroxy-2-(3-methoxypropyl)-2H-thieno[3,2- ] 1 2-thiazme-6-sulfonainide 1,1-dioxide ( 10 16 2 65 154127-42-1) see Brinzolamide ( )-3 ,4"-dihydro-r-hydroxy-7 -methoxyspiro[cyclOpen-tane-l,2 (l -naphthalene]-r-acetonitrile (CirHjiNO 57 797-09-9) see Butorphanol 23-dihydro-3 hydroxy-l methyl-l indole-5,6-dione (C9H9NO3 54-06-8) see Caibazochrome... 

Abbreviations EPR, electron paramagnetic resonance FITC, fluorescein-5 -isothiocyanate lAEDANS, iV-iodoacetyl-N -(5-sulfo-l-naphthyl)ethylenediamine NCD, fluorescent yV-cyclohexyl-N -(4-dimethyl-amino-a-naphthyl)carbodiimide RITC, rhodamine-5 -isothiocyanate DPPE, dipalmitoylphosphatidyl-ethanolamine PE, egg phosphatidyl-ethanolamine ANS, 8-anilino-l-naphthalene sulfonate DPH, diphenylhexatriene e-ADP, l,iV -ethanoadenosine-5 -diphosphate TNP-ADP, 2 [3 ]-0-(2,4,6-trinitrophe-nyl)adenosine-5 -diphosphate. 

The same authors studied the CL of 4,4,-[oxalylbis(trifluoromethylsulfo-nyl)imino]to[4-methylmorphilinium trifluoromethane sulfonate] (METQ) with hydrogen peroxide and a fluorophor in the presence of a, p, y, and heptakis 2,6-di-O-methyl P-cyclodextrin [66], The fluorophors studied were rhodamine B (RH B), 8-aniline-l-naphthalene sulfonic acid (ANS), potassium 2-p-toluidinylnaph-thalene-6-sulfonate (TNS), and fluorescein. It was found that TNS, ANS, and fluorescein show CL intensity enhancement in all cyclodextrins, while the CL of rhodamine B is enhanced in a- and y-cyclodextrin and reduced in P-cyclodextrin medium. The enhancement factors were found in the range of 1.4 for rhodamine B in a-cyclodextrin and 300 for TNS in heptakis 2,6-di-O-methyl P-cyclodextrin. The authors conclude that this enhancement could be attributed to increases in reaction rate, excitation efficiency, and fluorescence efficiency of the emitting species. Inclusion of a reaction intermediate and fluorophore in the cyclodextrin cavity is proposed as one possible mechanism for the observed enhancement. 

Source Schauer et al. (1999) reported naphthalene in diesel fuel at a concentration of 600 pg/g and in a diesel-powered medium-duty truck exhaust at an emission rate of 617 pg/km. Detected in distilled water-soluble fractions of 87 octane gasoline (0.24 mg/L), 94 octane gasoline (0.21 mg/L), Gasohol (0.29 mg/L), No. 2 fuel oil (0.60 mg/L), jet fuel A (0.34 mg/L), diesel fuel (0.25 mg/L), military jet fuel JP-4 (0.18 mg/L) (Potter, 1996), and used motor oil (116 to 117 pg/L) (Chen et al, 1994). Lee et al. (1992) investigated the partitioning of aromatic hydrocarbons into water. They reported concentration ranges from 350 to 1,500 mg/L and 80 to 300 pg/L in diesel fuel and the corresponding aqueous phase (distilled water), respectively. Diesel fuel obtained from a service station in Schlieren, Switzerland contained 708 mg/L naphthalene (Schluep et al, 2001). 

This synthetic fiexibility was put to use in the preparation of " C-labeled isotopomers of duloxetine (3) for further biological studies (Scheme 14.12). Labeled thiophene carboxylic acid 40 was readily converted to radioactive intermediate 43a, which was then converted to duloxetine-[3- " C] hydrochloride (3a ) via route A. In contrast, 43b was submitted to route B, utilizing labeled [l- C]-naphthalene, to provide duloxetine-[l-naphthalene- " C] hydrochloride (3b ). 

As one of the probes, fluorescence compounds are known. The fluorescence probe such as 8-anilino-l-naphthalene sulfonic acid ammonium salt(ANS) has been used as an indicator of membrane... 

The melting points of some nitrophenylazo-l-naphthalene derivatives are given in Table I. 

Phenolic ethers, dealkylation of, 287 Phenols, nitrosation of, 394 Phenoxypropadiene, 11 3-Phenylamino-l-butyne, 97 Phenyl azide, 281-282 Phenylazoalkanes, 327 Phenylazodiphenylphosphine oxide, 328 Phenylazoethane, 308 Phenylazohydroperoxides, 331 2-Fhenylazo-l,3-indandione, 299 Phenylazo-l-naphthalene, 304, 311 PhenyIazo-2-naphthaIene, 304, 311 Phenylazonaphthalenes, 310... 

Among the dopes used may be cited the following combustibles colophony (used by Nobel in his Dynamites of 1869 1873) (Vol 3 of Encycl, p C403R) wood-meal, woodpulp and sawdust in Grisounite and in some Amer Dynamites cork,charcoal (in "Carbodynamite , described in Ref 60, p C52-L) naphthalene (in Rheinischdynamit) and cotton or other forms of cellulose (in "Forcites ). Less frequently have been used peat moss, ivoty nut meal, unbaked com flakes, starch, pulverised peanut hull, pulverized cottonseed hulls and sunflower seed shells... 

Suzuka, T., et al. 1986. Effects of phenothiazines and /V-(6-aminohexyl)-5-chloro-l-naphthalene-sulfonamide on rat colonic absorption of cefmetazole. J Pharmacobiodyn 9 460. 

Irradiation of 3-hydroxy-2-naphthalenemethanol and 2-hydroxy-l-naphthalene-methanol results in efficient dehydration and the formation of isomeric naphthoquinone methides, 2,3-naphthoquinone-3-methide and 1,2-naphthoquinone-1-methide,... 

Chemical Name 4-Methoxy-6-oxo-l-naphthalene butanoic acid... 

Pravastatin was isolated as products of enzymatic hydroxylation by some kinds of microorganisms of [lS-[l-a(R ),7p,8P(2S, 4S )8a 3]]-2-methylbutanoic acid l,2,3,7,8,8a-hexahydro-7-methyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2))-pyran-2-yl)ethyl]-l-naphthalenic lactone (campactin) or their carboxylic acid or their salts (products of animal metabolism of microorganisms from the genera Nocardia, Streptomyces et cetera). 

Figure 42. 8-Anilino-l-naphthalene sulfonic acid (ANS) binding assay of the protyrosinase (pro-TY, —) and acid-activated tyrosinase (acid T Y, —).

Also, HPLC methods with electrochemical or fluorescent detection are used (H19, M3). In proteins, dityrosine can be estimated by immunochemical methods employing dityrosine-specific antibodies (K5). Measurements of o,o -dityrosine and o-tyrosine levels in rat urine express dityrosine contents in skeletal muscle proteins, and have been proposed as the noninvasive oxidative stress test in vivo. One should be aware, however, that A-formylkynurenine, also formed in protein oxidation, has similar fluorescence properties as dityrosine (excitation 325 nm, emission at 400-450 nm) (G29). Also, oxidation of mellitin when excited at 325 nm produces an increase in fluorescence at 400—450 nm, despite the fact that mellitin does not contain tyrosine. Oxidation of noncontaining Trp residues ribonuclease A and bovine pancreatic trypsin inhibitor with "OH produces loss of tyrosine residues with no increase in fluorescence at 410 nm (S51). There are also methods measuring the increased hydrophobicity of oxidized proteins. Assays are carried out measuring protein binding of a fluorescent probe, 8-anilino-l-naphthalene-sulfonic acid (ANS). Increase in probe binding reflects increased surface hydrophobicity (C7). 

Scheme 6. Preparation of pentasaccharide 11 [42] (a) galactose oxidase Dactylium dendroides), catalase (bovine liver), phosphate buffer, 37 °C (b) 5-(2-aminoethylamino)-l-naphthalene-sulfonate (EDANS), MeOH, reflux, then NaBHjCN...

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