Killer cell immunoglobulin

Immune Defense. Figure 2 Cytokines involved in the development of adaptive immune responses in secondary lympoid tissues such as the lymph nodes or spleen. Abbreviations B B-lymphocyte, IFN interferon, Ig immunoglobulin, IL interleukin, NK natural killer cell, TE T-effector (cytotoxic) lymphocyte, TH T-helper lymphocyte... 

Immunotoxicity. The data in humans are limited to a few studies of immune function in lead workers and a study of firearm instructors. In both type of studies, inhalation is assumed to be the primary route of exposure. One study reported significant suppression of IgA levels (Ewers et al. 1982). Another study indicated that serum immunoglobulin levels were not significantly altered (Alomran and Shleamoon 1988). Another large study examined several parameters of immune function (serum immunoglobulins, PHA response, and natural killer cell activity) and found no differences in exposed workers and controls (Kimber et al. 1986b). The study of firearm instructors found functional impairment of cell-mediated immunity in subjects with PbB levels >25 pg/dL (Fischbein et al. 1993). A recent study that evaluated a... 

Boyton R-J, Altmann DM Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class 1 in disease. Clin Exp Immunol 2007 149 1-8. 

IGIV Immunoglobulin intravenous LAK cell Lymphokine-activated killer cell LFA Lymphocyte functional antigen MAb Monoclonal antibody MHC Major histocompatibility complex MCP-1 Macrophage chemotactic protein-1 MIP-1 Macrophage inflammatory protein-1 NK cell Natural killer cell... 

Colonna, M. (1997). Immunoglobulin superfamily inhibitory receptors From natural killer cells to antigen-presenting cells. Res. Immunol. 148(3), 169-171. 

KIRs killer immunoglobulin like receptors are MHC-binding receptors on NK cells that diggers NK cell-mediated responses. KIRs diversify human natural killer cell populations... 

Null cells are a separate subset of lymphocytes that lack surface markers of B or T origin. These cells, also referred to as large granular lymphocytes, are thought to perform functions such as direct cytotoxicity to foreign entities, and they act either alone (natural killer cells) or in concert with immunoglobulin (antibody-dependent cellular cytotoxicity). (Further details regarding lymphocytes are found in Chap. 84, on the immune system.)... 

ASCs, antibody-secreting cells CTLs, cytotoxic T lymphocytes IFN, interferon Ig, immunoglobulin IL, interleukin MHC, major histocompatibility complex TNF, tumor necrosis factor NK cells, natural killer cells. 

CD45 RA, naive memory T eells CTL, eytotoxie T lymphocytes HLA, human leukocyte antigen IgA, IgG, IgE, immunoglobulin A, G, E IL, inter-leukin NKC, natural killer cells TNF, tumor-necrosis factor, ZPP, zinc protoporphyrin. 

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