KATHON WT

KATHON WT Cooling Tower, Air Washer and Papermill Slimicide 

Microbiocides and slimicides for industrial cooling tower water, air washers and papermill process water. 

KATHON WT and WT 1.5% microbiocides offer a number of outstanding advantages  

The active ingredient of KATHON WT and KATHON WT 1.5% microbiocides is a mixture of two isothiazolinones identified by the lUPAC system of nomenclature as  

---

KATHON WT is a commercialized biocide product created by Rohm and Haas Ltd. 

Next, FIBCIDE-KF containing Cl-MIT (3 wt%) was tested as an additive to a coating material for printer paper. The coating material was unaffected by the addition of FIBCIDE-KF, but coagulation occurred when KATHON WT was added instead (Figure 9). Since KATHON-WT contains Mg salts, whereas FIBCIDE-KF does not, it is thought that this was the cause of the problems with coagulation. 

Further to these results, the microbicidal activities of FIBCIDE-KF and KATHON WT were evaluated. The minimum inhibitory concentrations (MIC) for Pseudomonas aeruginosa, Pseudomonas putida, Bacillus subtilis and Microbacterium sp. are identical for both compounds, so the microbicidal effect has not diminished (Figure 10). It appears that the biocidal effects are similar because the Cl-MIT in the inclusion complex is released into water, as shown in Figure 6. 

Cl-MIT was prepared by extraction from KATHON WT. KATHON WT (500 mL) was extracted with chloroform (2 x 100 mL). The chloroform solution was washed with water, dried (Na2S04) and evaporated to give an extract of Cl-MIT. The purity of Cl-MIT in the extract was measured by HPLC. 

Based on the scores over 72 hours (Table 7), the primary irritation index (PII) for FIBCIDE-K58 is 0.7, with a descriptive rating of slight irritation . On the other hand, the PII for KATHON WT is 8.0, with a descriptive rating of severe irritation. 

Table 7 Primary dermal irritation scores of FEBCIDE-K58 and KATHON WT.

Uses Antimicrobial, biocide, preservative for metalworking fluids, polymer emulsions, cooling tower water treatment, paints, topical pharmaceuticals slimicide for paper mills food-pkg. adhesives in paper/paperboard in contact with aq./fatty foods Regulatory FDA 21CFR 175.105, 176.170 Trade Name Synonyms Kathon 886 f[Rohm Haas http //www.rohmhaas.com] http //www.acusol.com]] Kathon 886 MW [Rohm Haas http //www.rohmhaas.com] http //www.acusol.com] Rohm Haas France] Kathon CG/ICP [Rohm Haas http //WWW. rohmhaas. com] http //www.acusol.com]] Kathon LX [Rohm Haas http //www.rohmhaas.com] http //www.acusol.com]] Kathon WT [Rohm ... 

Bruze M, Dahlquist I, Gruvberger B (1990) Chemical burns and allergic contact dermatitis due to Kathon WT. Am J Contact Dermat 1 91-93... 

O Driscoll JB, Beck MH ( 88) Occupational allergic contact dermatitis from Kathon WT. Contact Dermatitis 19 63 Pilger C, Nethercott JR, Weksberg F (1986) Allergic contact dermatitis due to a biocide containing 5-chloro-2-methyl-4-isothiazolin-3-one. Contact Dermatitis 14 201-204 Piraccini BM, Peluso A, De Maria P, Tosti A (1991) Occupational contact dermatitis due to the disinfectant Tego Diocto S . Contact Dermatitis 24 228-229... 

Shehade S, Beck M, Muston H (1990) Industrial sensitization to Kathon WT and organic bromide compounds used as slimicides in the paper industry. Contact Dermatitis 21 247... 

---