Japan Association for International Chemical

Nuclear Quadrupole Resonance Spectra Database, Japan Association for International Chemical Information, Tokyo (2003). 

There has been a rapid proliferation of commercial search interfaces, such as DataStar and STN International. STN may deserve special mention since it is a science information service operated by Chemical Abstracts Service (CAS) in North America, Fachinformationszentrum-Karlsruhe (FIZ-K) in Europe, and Japan Association for International Chemical Information (JAICI) in Japan. It is available as online subscriber access to 220 databases (STN Express) and as web access (STN on the Web for experienced searchers and STN Easy for infrequent searchers). See www.cas.org/stn. html and/or www.stn-international.de/. Since Internet search techniques depend on the interface available, no detailed explanations are given here. There are several published guides to database searches for chemical and physical properties, but the situation is evolving rapidly and it is recommended that you consult a reference librarian for information about the current situation concerning search interfaces at the library you use. 

References for articles reporting results of ab initio quantum chemical calculations on different properties of aniline and derivatives can be retrieved from the compilation Quantum Chemistry Library Data Base (QCLDB), Japan Association for International Chemical Information, Tokyo, Japan, 2005. 

Almost all quadrupolar nuclei in the Periodic Table have been studied experimentally in one or more of their compounds. A current list 0f these results is available in a database published by the JAICI (Japan Association for International Chemical Information, Tokyo, Japan). Biennial International Symposia on nuclear quadrupole interactions are also excellent sources of the latest experimental and theoretical works. As an illustration of the kind of solid-state problems that may be studied, we give some recent examples of such investigations. Sensitivity. or signal-to-noise ratio (SNR) in WQR spectroscopy, as well as NMR, depends on the observed frequency, which in turn, depends, inter alia, on the value of Q. The lighter elements tend to have low values of Q and low NQR frequencies and low sensitivities. for example, a... 

MOPAC 6.0 (QCPE 455, JCPE 44, 49). Inquiry addresses QCPE, Creative Arts Bldg. 181, Indiana University, Bloomington, IN 47405, USA JCPE, c/o Japan Association for International Chemical Information, Gakkai Center Bldg., 2-4-16 Yayoi, Bunkyo-ku, Tokyo 113, Japan. 

Japan Association for International Chemical Information Nakai Building, 6-25-4 Honkomagome, Bunkyo-ku Tokyo 113,Japan... 

In other parts of the world, reference journals were also founded In 1927, the first issue of the journal Nippon Kagaku Soran was published in Japanese. This journal has abstracted the Imown chemical literature in Japan since 1877. The Japan Information Center of Science and Technology (JICST), which was founded 1957, took over the reference journal in 1958 for financial reasons and continued publishing it with the new title Domestic Chemistry Series of JICST Current Awareness. The rest of the world did not take very much notice of Japanese publications, now and then an article was cited in Chemisches Zen-tralblatt or Chemical Abstracts although this Japanese reference journal was essential for Japanese chemists. The number of publications, which were cited in Chemical Abstracts increased steadily (34 abstracts in 1907 109,800 in 1991), the systematic access to the Japanese chemical literature was organized after the Second World War Since 1977, the Japan Association for International Chemical Information (JAICI), a department of JICST, has cooperated with Chemical Abstracts Service and since 1980, all CA abstracts of Japanese publications have been written by JAICI. 

The most influential of these test protocols are the USP, - the European Pharmacopoeia (EP), the Pharmacopoeia of Japan (JP), - the Organization for International Standardization (ISO), and the Parenteral Drug Association (PDA). ° USP<381>, Elastomeric Closures for Injections, contains five chemical tests and two biological tests. Closures must meet the biological requirements but there are no current specifications for the chemical tests. All USP chemical tests are commonly performed on aqueous extracts but isopropyl alcohol and the drug product vehicle are also permitted. A brief description of the USP<381> tests follows. ... 

Prof. Rao is Chairman, Scientific Advisory Council to the Prime Minister, past President of The Academy of Sciences for the Developing World (TWAS), Member of the Atomic Energy Commission of India and Chairman, Indo-Japan Science Council. He is Founder-President of both the Chemical Research Society of India and of the Materials Research Society of India. Prof. Rao was President of the Indian National Science Academy (1985-86), the Indian Academy of Sciences (1989-91), the International Union of Pure and Applied Chemistry (1985-97), the Indian Science Congress Association (1987-88), and Chairman, Advisory Board of the Council of Scientific and Industrial Research (India). He was the Director of the Indian Institute of Science (1984-94), Chairman of the Science Advisory Council to Prime Minister Rajiv Gandhi (1985-89) and Chairman, Scientific Advisory Committee to the Union Cabinet (1997-98) and Albert Einstein Research Professor (1995-99). 

The safety-toxicological testing of a new excipient for Europe or the United States is as extensive as that for an NCE and can take four to five years to complete. There are differences in the safety evaluation requirements for different types of formulations oral, parenteral and topical/transdermal. The International Pharmaceutical Excipients Council (IPEC Europe and IPEC-Americas) have been working on a protocol for the rational safety testing of excipients to aid the introduction of new chemical excipients (see Table 5.4). IPEC is a federation of three independent regional industry associations based in Europe, the United States and Japan who are focused on the applicable law, regulations and business practices of each region with respect to pharmaceutical excipients. 

Shiba, Tetsuo (p. 222, Plate 43) born in Hiroshima Prefecture, Japan in 1924, received his Ph.D. degree at Osaka University in 1959. After having studied at the National Institute of Health, Bethesda, USA, as Visiting Scientist for two and a half years, he returned to Osaka University as Associate Professor in 1962. In 1971 he was appointed Professor, Laboratory of Natural Product Chemistry, Department of Chemistry, Faculty of Science, Osaka University. Here he developed his structural and synthetic studies on biologically active substances (peptides and others). In the meantime, he served as Vice President of the Chemical Society of Japan, and now as a Member of the Science Council of Japan. He successfully planned the Japan Symposia of Peptide Chemistry and the first international Symposium of Peptide Chemistry in Japan as President of the Organizing Committee in 1987. 

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