Isoflavones chemistry

Liu, K. Soy isoflavones chemistry, processing effect, health benefits, and commercial production. Soybeans as Functional Foods and Ingredients K. Liu, Ed., AOCS Press Champaign, IL, 2004b pp. 52-72. 

K. Wahala, S. Deb and T. Hase, The Stmcture of Isoflavones ly ID and 2D Homonuclear and Heteronuclear NMR Spectroscopy, n Isoflavones Chemistry,... 

Toro-Funes N. Odriozola-Serrano I. Bosch-Fuste J. Latorre-Moratalla M.L. Veciana-Nogues M.T. Izquierdo-Pulido M. Vidal-Carou M.C. Fast simultaneous determination of free and conjugated isoflavones in soy milk by UHPLC-UV. Food Chemistry, 2012, 135, 2832-2838. 

Abd El-Latif, R.R. et al., A new isoflavone from Astragalus peregrinus. Chemistry of Natural Compounds (Translation of Khimiya Prirodnykh Soedinenii), 39, 536, 2003. 

Elgindi, M.R. et al., Isoflavones and a phenylethanoid from Verbascum sinaiticum, Asian Journal of Chemistry, 11, 1534, 1999. 

Kudou, S. et al., A new isoflavone glycoside in soybean seeds Glycine max Merrill), glycitein 1-0-P-D-(6"-0-acetyl)-glucopyranoside, Agricultural and Biological Chemistry, 55, 859, 1991. 

Saxena, V.K. and Mishra, L.N., A new isoflavone glycoside from the roots of Sesbania grandi-flora. Research Journal of Chemistry and Environment, 3, 69, 1999. 

Yuldashev, M.P. et al.. Structural study of glabrisoflavone, a novel isoflavone from Glycyrrhiza glabra L., Russian Journal of Bioorganic Chemistry (Translation of Bioorganicheskaya Khimiya), 26, 784, 2000. 

Caldwell CR., Britz SJ., Mirecki RM. Effect of temperature, elevated carbon dioxide, and drought during seed development on the isoflavone content of dwarf soybean [Glycine max (L.) Merrill] grown in controlled environments. Journal of Agricultural Food Chemistry 2005 53(4) 1125-1129. 

Scheme 3 presents substrates which carry both electron-donating and electron-withdrawing substituents. These systems, in comparison with the previous set of substrates, were considerably less reactive so that longer reaction times and excess oxidant were necessary for complete epoxidations. In the rosette are displayed the oxidation of p-oxo enol phosphates [13] 13, dihydrofuranone [17] 14, p-alkoxycyc-lohexenones [17] 15, alkoxymethylenecyclohexanones [17] 16, benzalphthalide [12a] 17, aurones [18] 18, flavones [19] 19, and isoflavones [18] 20. Many of these epoxides, which have become available for the first time, constitute valuable building blocks for natural product chemistry. 

Wu, J., Muir, A. D. (2008). Isoflavone content and its potential contrihntion to the antihypertensive activity in soybean angiotensin I converting enzyme inhibitory peptides. Journal of Agricultural and Food Chemistry, 56, 9899-9904. 

Based on these facts, in 2008, first, a group of H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Pakistan examined a benzil and isoflavones (2) from... 

In studies of the chemistry of compounds of this class it was shown that treatment of the chalcone (60) with thallium(iii) nitrate gave the isoflavone (61).i<">... 

Fig 2.1 Early contributions to the flavonoid chemistry of the Leguminosae. The isoflavone glucoside, ononin (1), first obtained from the roots of Ononis spinosa (spiny restharrow) by Reinsch in 1842. Robinin (2), a flavonol 3,7-O-glycoside from the flowers of Robinia pseudoacacia (black locust tree), first mentioned in the literature by Zwenger and Dronke in 1861. 

Noguchi, A., Saito, A., Homma, Y. et al. (2007). A UDP-glucose isoflavone 7-O-glucosyltiansfer-ase from the roots of soybean Glycine max) seedlings. Journal of Biological Chemistry, 282, 23581-23590. 

Yokosuka, A., Haraguchi, M., Usui, T. et al. (2007). Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. Bioorganic and Medicinal Chemistry Letters, 17, 3091-3094. 

Jackman, K.A., Woodman, O.L. Sobey, C.G. (2007). Isoflavones, equol and cardiovascular disease pharmacological and therapeutic insights. Current Medicinal Chemistry, 14, 2824-2830. 

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