Insomnia methylphenidate

The side effects of methylphenidate are very similar to the amphetamines, but because it is somewhat less potent they may be a little milder. The common side effects of methylphenidate are appetite loss, weight loss, insomnia, and nausea. Taking methylphenidate with meals and no later than 6 PM can control most of these. On rare occasions, methylphenidate can cause headache, dizziness, nervousness, increased heart rate, increased blood pressure, tics, and, in extremely rare cases, paranoia. 

Adverse reactions with other methylphenidate hydrochloride products -Nervousness and insomnia are the most common adverse reactions reported with other methylphenidate products. In children, loss of appetite, abdominal pain, weight loss during prolonged therapy, insomnia, and tachycardia may occur more frequently however, any of the other adverse reactions listed also may occur. 

Methylphenidate also has been combined with clon-idine, the a.2 agonist, to reduce aggression, to provide better control of ADHD symptoms after the stimulant wears off, and to counteract insomnia associated with stimulant treatment (Wilens et ah, 1994). The report of four deaths on the Federal Drug Administration (FDA) s MEDWATCH surveillance network, however,... 

Even when effective in controlling behavior, Ritalin and other stimulants have side effects common with use of amphetamines. These include nervousness, insomnia, and perhaps some more long-term problems such as dependency, slowed growth, or depression. Critics sometimes note the similarity between cocaine and the active chemical ingredient in Ritalin, methylphenidate. Both stimulate the dopamine system of the brain, but cocaine does so quickly and methylphenidate does so slowly. The similarities show in the abuse of Ritalin for its pleasure-inducing qualities. 

The primary drug therapies are psychostimulants which are indicated for both emotional based sleep disorders (i.e., narcolepsy) as well as ADHD. The drugs of choice are Ritalin (methylphenidate), dextroamphetamine or Cylert (pemoline), all CNS stimulants that effect the monoamine systems. The current therapies provide symptomatic relief but the current medications are not without side effects, including abuse potential, cardiovascular effects, insomnia, appetite suppression, head and stomach aches, crying and nervous mannerisms. 

The adverse effects associated with methylphenidate are generally mild and short-lived, with the most common effects being insomnia, decreased appetite, stomach ache, headache, and jitteriness. Although methylphenidate has been abused, the problem of abuse is generally seen in adults who use multiple substances or in adolescents experimenting with medications (28). Sweden withdrew methylphenidate from its market in 1968 because some adults dissolved tablets and injected the solution, leading to serious cases of talc granulomatosis (38). However, most cases of methylphenidate abuse apparently have led to less serious consequences (28). 

As with methylphenidate, the adverse effects associated with pemoline are generally mild. The most common effects are insomnia, decreased appetite, stomachache, headache, and jitteriness (28). Periodic monitoring of liver enzymes is necessary because of the potential for hepatic toxic effects. 

Methylphenidate (Ritalin Ritalin SR Concerta Metadate) doses range from 5 mg/day bid to a maximum of 60 mg/day, divided fid. Side effects include nervousness, insomnia, loss of appetite and headaches. 

Q7 Side effects of methylphenidate are appetite suppression, nausea, abdominal pain, nervousness, irritability and insomnia. The patient s blood pressure needs to be checked as use of the drug may involve headaches and dizziness. In the long term, the medication may affect a child s height and weight and his growth should be monitored during prolonged treatment. The effectiveness of the medication should also be reassessed before the onset of puberty. 

Side effects of modafinil include headache, nausea, nervousness, and insomnia. Amphetamines and methylphenidate have a fast onset of effect and durations of 3 to 4 hours and 6 to 10 hours, respectively, for excessive... 

Methylphenidate is a piperidine derivative, structurally related to amphetamine, but a milder central nervous system stimulant. However, large doses produce symptoms of generalized central nervous system stimulation and convulsions. It is more active than amphetamine as an antidepressant, as a treatment for overdosage of depressant drugs, and in exacerbating schizophremc symptoms. Occasionally, anorexia, nausea, dry mouth, nervousness, insomnia, dizziness, and palpitation have been recorded. 

A modified-release, once-daily formulation has been evaluated in 282 children with ADHD in a double-blind, placebo-controUed trial for 28 days (37). For core ADHD symptoms, both once-daily modified-release and thrice-daily immediate-release methylphenidate were superior to placebo and not different from each other. A similar percentage of patients reported at least one adverse event with both formulations. The most commonly reported adverse events were headache and upper respiratory infections, followed by abdominal pain, cough, pharyngitis, vomiting, and otitis media. Of these, only headache and abdominal pain were considered to be related to the study medication. One patient withdrew because of depression with modified-release methylphenidate and one because of tics with placebo. Headache occurred in 14%, 5.8%, and 10% of patients taking modified-release methylphenidate, immediate-release methylphenidate, or placebo respectively, and abdominal pain in 6.7%, 5.8%, and 1.0%. Other adverse events included appetite suppression (modified-release methylphenidate) and insomnia (aU three). The results of this study suggest that once-daily modified-release methylphenidate provides efficacy superior to placebo and is not significantly different from thrice-daily immediate-release methylphenidate. 

Stimulants have been used as antidepressants for many years, especially dextroamphetamine (Dexedrine) and methylphenidate (Ritalin). They have the side effects of anxiety, insomnia, agitation, and appetite suppression. They can be quite effective antidepressants but are now usually reserved for medically ill patients such as those who have had a stroke and those unresponsive to other antidepressants. 

S-methylhomocy teine methionine, methylisogenistin genistein. /V-methylmescaline mescaline, methylmorphine codeine, a-methy I noradrenaline levonordefrin. methyl pentynol (ban. inn] is an acetylenic carbinol. with HYPNOTIC and SEDATIVE properties. It has been used in the treatment of insomnia and as an anxiolytic. methyl-PGEj arbaprostil. methylphenidate [ban, inn] (methylphenidate hydrochloride [jan, usan] Ritalin ) is a CNS STIMULANT and dopamine (re) UPTAKE INHIBITOR. It is used in the treatment of attention-deficit hyperactivity disorder in children, methylphenidate hydrochloride methylphenidate. 

Sometimes doctors prescribe methylphenidate (Ritalin) or dextroamphetamine (Dexedrine) to treat a mood disorder called dysthymia that is less severe, but more chronic, than major depression. They work more quickly than antidepressants to pep you up, increasing energy and facilitating attention and concentration. Common side effects include nervousness, insomnia, constipation, headache, and changes in heart rate. 

Comparative trials Non-stimulant medications are being evaluated for the treatment of attention deficit hyperactivity disorder (ADHD) in children and adolescents as alternatives to stimulants. In these studies reduced appetite and restlessness were more common with methylphenidate than with amantadine [54 ], and headache and insomnia were more common with methylphenidate than with venlafaxine [55 ]. Nevertheless, these studies do not constitute proof of efficacy. 

In an open study in children aged 6-17 years the addition of OROS methylphenidate increased the rates of insomnia, irritability, and loss of appetite compared with atomoxetine alone [M ]. 

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