Insecticidal metabolites

McCarthy, A.R., Thomson, B.M., Shaw, I.C., and AbeU, A.D. (2006). Estrogenicity of pyre-throid insecticide metabolites. Journal of Environmental Monitoring 8, 197-202. 

EPA research investments since 1995 in pesticide exposure and risk assessment methods have helped pioneer novel approaches to quantify risk levels. A team at the University of Washington s School of Public Health and Community Medicine found that 2-5 year olds consuming predominantly organic foods over a 3-day period had 8.5-fold lower mean levels of OP insecticide metabolites in their urine than children eating mosdy conventional (unlabeled) foods (Curl et al., 2003). The study was carefully designed to minimize potentially... 

All 23 children had OP insecticide metabolites in their urine in phase one testing, while levels were below the limit of detection during phase two, following the consumption of mostly organic food for just five days. Once the children were back on their normal, conventional food in phase three, the levels of insecticide metabolites in urine returned to those found in phase one. 

Environmental Defence recently released Toxic Nation A Report on Pollution in Canadians (Environmental Defence 2005). Samples were collected from 11 people for the presence of 88 chemicals, including heavy metals, PBDEs, PCBs, perfluorinated chemicals, organochlorine pesticides, organophosphorus-insecticide metabolites, and VOCs. The study objectives included determining whether pollutants were present at measurable concentrations in Canadians, identifying chemicals of concern, and creating public awareness of methods for avoiding exposure. 

Organophosphate insecticide metabolites Breakdown products of organophosphate insecticides. Have been found in urine of adult farmworkers and children exposed to the organophosphate residues. 

Insecticidal Metabolites from Fusarium avenaceum, a Fungus Associated with Foliage of Abies balsamea Infested by Spruce Budworm, Choristoneura fumiferana... 

Isoechinulins A, B, and C (22-24) have been isolated from the mycelium of Asp. ruber by Tamura and co-workers (37,48,53), in the course of screening for insecticidal metabolites of fungi. Among them, isoechinulin A causes growth inhibition of silkworm larvae (Bombyx mori L.) by oral administration at a concentration of 1000 ppm. 

Within this context, an interesting methodology using UPLC-QTOE-MS has been developed to achieve this purpose. Hernandez et al. [117] were able to evaluate the potential of the UPLC-MS technique for the characterization of phosmet (organophosphate insecticide) metabolites in VOO positives samples. 

Alarif WM, Abou-ElnagaZS, Ayyad SEN, Al-lihaibi SS (2010) Insecticidal metabolites from the green alga Caulerpa racemosa. Clean Soil Air Water 38(5-6) 548-557... 

Myokei, R., Sakurai, A., Chang, C.F., Kodaira, Y, Takahashi, N., and Tamura, S. (1969) Structure of aspochracin, an insecticidal metabolite of Aspergillus ochraceus. Tetrahedron Lett., 10, 695-698. 

Okada, A., Watanabe, K., Umeda, K., and Miyakado, M. (1991) Calyculin E and F, novel insecticidal metabolites from the marine sponge, Discodermia sp. Agric. Biol Chem., 55, 2765-2771. 

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