Immediate pack

Drug product should be exposed to light conditions as stated above. The testing should be done in a sequential manner with fully exposed drug product and as necessary followed by testing the product in the immediate pack and then in the... 

A configuration for presenting tablets or capsules in their immediate pack for photostability testing is shown in Figure 16. 

Marketing pack This is the combination of immediate pack and other secondary packaging, such as a carton. 

The term pack in the above covers all the components involved, i.e. the primary or immediate pack which consists of those materials in direct contact with the product. The secondary pack and sometimes tertiary components enable the product to be stored, transported and displayed, and possibly assist use. Tertiary components may include ancillary components, e.g. leaflets or inserts, separate dispensing spoons and measures. 

The formulation and packaging disciplines have carried out adequate investigation or feasibility support work to establish the functional and aesthetic aspects of the pack, both primary and secondary. The primary pack (US terminology—immediate pack) may be defined as the pack which is in immediate contact with the product, and the secondary pack as the ancillary materials required for presentation, information, warehousing and distribution purposes. Feasibility or investigational work may involve information-gathering on the pack and its components, etc. (i.e. basic research into materials, packs and processes) and compatibility studies, accelerated or otherwise, on the product and pack. 

Pack where administration component forms part of the primary or immediate pack and where some components are in... 

For some products where it has been demonstrated that the immediate pack is completely impenetrable to light, such as aluminium tubes or cans, testing should normally only be conducted on directly exposed drug product. 

Tests on the exposed drug product outside the immediate pack... 

The most common agglomeration technology for the conversion of sodium cyanide into a safe product is briquetting with roller presses. Almond- or pillow-shaped compacts are made. The systems are completely enclosed, equipped with highly effective dust collection systems to safeguard the operators, and executed in stainless steel to keep corrosion in check. The discharge from the roller press is screened within the enclosed system, fines are recirculated internally to the briquetter feed bin, and dean product is immediately packed into sealed containers. 

A special mixture used in pies, coffee cakes, and cookies. It is made with raisins, citron, apple, sugar and spices and usually contains some cooked beef and suet, which has been put through the food chopper along with the apple. The whole mixture is then simmered together. It can be used immediately, packed in sterilized jars, or put in the freezer. 

Flakes are formed on a rotating drum with internal cooling, partially submersed in the melt. The layer of solidified NaOH is scrapped off from the drum by a knife and milled, giving the flakes, which are cooled further down and immediately packed in bags or drums. 

The diets consisted of 4 types of beet pulp Root or top fractions from Angus sugar beet (A) or Colosse fodder beet (C). The pulp was prepared by a cold mechanical pressing of the cut root or top fractions. Daily rations were immediately packed and stored at -18 °C. 

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