Marketing packs

They should also have been trained on the particular machines that are on the packaging line, particularly in safety and observation, and have a thorough knowledge of how the marketable pack should look at all stages of its packaging. There should be codes of dress, discipline, line cleandown procedures, and other operating procedures in which the operators have been trained. These should also be readily available nearby so that they may be referred to at any time. 

Note Many of values are those listed in vendors literature and are frequently based solely on pilot tests. It may be prudent on occasion to assume slightly larger packing factors in order to represent more precisely the pressure drop of newly marketed packing in commercial columns. Consult with vendors for data on newer, proprietary packings. 

Marketing pack This is the combination of immediate pack and other secondary packaging, such as a carton. 

If necessary, tests on the drug product in the marketing pack [ICH Q1B]... 

If changes that are observed are acceptable only when the product in the market pack is exposed under the conditions described in the Q1B guidance, labeling storage statements regarding fight should be included. 

Curare is the name given to the South American arrow poisons prepared from extracts of local plants by Indian tribes who dwell on the borders of Brazil, Peru, and Ecuador about the waters of the upper Amazon. The various curares are designated according to the containers into which they are packed. Tubo-curare, a dark red resinous mass is put into bamboo tubes, calabash-curare is packed in the gourd, and the pot-curare is brought to the market packed in tinted earthenware pots. The composition of the curare has been studied for a long time, but the amorphous nature of the constituents and the rarity of the crude native preparations have delayed progress in this field. 

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