Hydroxy amine

Supplement 1942 195-449 Hydroxy-amines Aminoethyl alcohol, 274. Carbonyl-amines Aminoacetaldehyde, 307. Aminoacetone, 314. Hydroxy-carbonyl amines Glucosamine, 328. Aminocarboxylic acids Glycine, 333. Hydroxylamines, 534. Hydrazines, 546. Azo Compounds. 562. Oryano-metallic Compounds, 580. 

Supplement (combined 1933 1740-1928 zidine, 314. Triamines, 294. Hydroxy-amines o-Aminophenol, 354. 

The reaction is generally believed to proceed via the formation of ionic acylam-monium intermediate compounds (Reaction 1, Scheme 2.27). The equilibrium constant of the acylammonium formation depends mostly on steric and resonance factors, while the basicity of the tertiary amine seems to play a secondary role.297 In die case of the less basic compounds, such as acidic phenols, and of strong tertiary amines, such as Uialkylamines, the reaction has been reported to proceed through a general base mechanism via the formation of hydroxy-amine H-bonded complexes (Reaction 2, Scheme 2.27).297... 

Hydroxy-amine H-bonded complexes, 76 Hydroxybenzoic acids, polyesterification of, 79... 

Using other alkylated benzene hydrocarbons, e.g., amyl-, hexyl-, octyl-, or nonylbenzene, similar surface-active phosphinic acids are formed by reaction with PC13 in the presence of anhydrous aluminum trichloride. The resulting alkylarylphosphinic acids form stable salts with primary, secondary, or tertiary hydroxy amines or aromatic amines [166,171]. 

Lactame ergeben mit Hydriden den Carbonsaure-amiden ahnliche Reduktionspro-dukte (s. S. 230). Der cyclischen Struktur entsprechend werden cyclische a-Hydroxy-amine und Amine, sowie unter Aufspaltung des Lactam-Ringes co-Amino-alde-hyde und [Pg.244]

Oxetanes are significantly less reactive with nucleophiles due to diminished ring strain. Under certain conditions, however, amines can open oxetanes to give amino alcohols. tert-Butylamine reacts with oxetanes in the presence of Yb(OTf)3 to give 3-hydroxy amines. Lithium tetrafluorohorate has also been used for this... 

Just as epoxides can be opened by amines to give hydroxy-amines, there are a limited number of examples of aziridines being opened to give diamines. Amines reacts with N-tosylaziridines, in the presence of Yb(OTf)3, to give the corresponding... 

An alternative strategy, avoiding the danger of over-reaction with diax.omethane, is to make the diazonium salt, by diazotisation of a hydroxy amine (14), available from the original ketone (12) via epoxide (13),... 

R, 25) -2- [(ethoxycarbonyl) amino] -1 -phenyl-1 -propanol [Brdnsted acid promoted reduction of c/-amino ketone to erythro a-hydroxy amine], 124-125... 

Hydroxy- amine H N-OH / H NH Ho. X N N H H 0 Anto-oxidation enhanced by metal ions Catalase/H202... 

Figure 3.1 Types of hydrogen bond in order of relative strength (from the left hydroxy-ether, hydroxy-amine and imino-amine)...

Isocyanates are quite reactive and they react with compounds which contain active hydrogen such as hydroxy, amine, carboxylic acids, amide, urea, etc. They can also undergo addition reaction ... 

NDE1A is not the only nitrosamine reported to have been identified in metalworking fluids. A fluid in the Netherlands was found to be contaminated with 5-methyl-N-nitrosooxazolidine (17). The two most likely explanations by which nitrosooxazolidines may be formed in metalworking fluids are (1) simple nitrosation of oxazolidine antimicrobials and (2) nitrosation of primary beta-hydroxy amines (18). The latter reaction is an example of the conversion of a primary amine into a nitrosamine. 

The phosphoramidic chloride (11) has been employed to phosphorylate phenols and alcohols, including carbohydrates.16 Other activity in phosphorylation chemistry has been mostly concentrated in two main areas. In the first of these, Japanese workers have continued their studies on the use of 2-substituted-4-nitrophenyl-phosphoric acids. The 7V-protonated form of the 2-dimethylamino-compound (12 R = Me) is a better phosphorylating agent than the corresponding 2-diethylamino-compound. The reaction of (12) with hydroxy-amines results in selective O-phos-... 

In the presence of samarium(II) iodide, A-(2-iodobenzyl)dialkylamines 347 react with electrophiles at an a-carbon atom to yield deiodinated products by way of intermediate samarium compounds 348. Thus TV-(2-iodobenzyl)diethylamine and pentan-3-one afford the hydroxy amine 349 and 7V-(2-iodobenzyl)pyrrolidine and propyl isocyanate give the amide 350390. 

Neamine is a derivative of neomycin B following acid-catalyzed hydrolysis. It represents the simplest of aminoglycosides with two potential sites of metal chelation (namely the 1,2-hydroxy-amine motif in either ring A or B). A 1 1 stoichiometric reaction of neamine with Cu(OAc)2 in MeOH, under refluxing conditions for 48 h, results in formation of a blue 1 1 Cu " "-neamine complex (kmax 712 mn, e 65 cm )." Extensive C-13 and H-1 NMR relaxation... 

Quadrol Poly(hydroxy amine) Wyandotte Chemicals... 

Several substituted hydroxy amines have been treated with acetylenic esters to give different heterocyclic systems. Thus, the reaction of o-aminophenol with diethyl acetylenedicarboxylate gives 3-carbethoxy-methylene-3,4-dihydro-2i/-l,4-benzoxazin-2-one (24) [Eq. (8)]. In... 

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