Hydrochloric acid interaction

The procedure is not usually applicable to aminosulphonic acids owing to the interaction between the amino group and the phosphorus pentachloride. If, however, the chlorosulphonic acid is prepared by diazotisation and treatment with a solution of cuprous chloride in hydrochloric acid, the crystalline chlorosulphonamide and chlorosulphonanilide may be obtained in the usual way. With some compounds, the amino group may be protected by acetylation. Sulphonic acids derived from a phenol or naphthol cannot be converted into the sulphonyl chlorides by the phosphorus pentachloride method. 

Attack on the electrophilic C-2 may occur as in the 2-aminothiazoles series, which probably explains the rearrangements observed in acidic medium (121, 711, 712, 723, 724), in aqueous medium with NaOAc (725), or with aqueous NaHCOj (725) (Scheme 232). That the initial attack probably involves the C-2 atom is substantiated by the fact that this rearrangement occurs under extremely mild conditions for 2-iinino-3-substituted-5-nitro-4-thiazolines (725). As the whole mechanism proposed (see p. 92) is reversible, when imino derivatives are submitted to such rearrangement conditions the rearrangement is expected to occur faster if steric interaction between 3- and 4-substituents exists in the 2-imino isomer. Another reaction may occur in acidic medium phenylimino-2-bipheny]-3,4-4-thiazoline hydrolyzed with hydrochloric acid gives the corresponding 4-thiazoline-2-one and aniline (717). 

McConnell and Weaver, using the nmr line width method, have obtained a value for the observed rate coefficient, for the reaction in 12 M hydrochloric acid media, of 5 x 10 l.mole . sec. The width of the Cu NMR line from copper(I) ( 1 M) was observed in the presence of copper(II) (10 to 10 M). In this media the exchanging species are probably CuCl4 and CuCls . Optical interaction effects have been observed in mixtures of Cu(I) and Cu(II) in chloride media. ... 

Moore ° has made a brief study of the slow reduction of U(VI) by Sn(II) in hydrochloric acid media. Chloride ion has a pronounced effect on the rate. Spectrophotometric evidence is cited for the complexing interaction of U(VI) and Sn(II). 

There are two explanations for the small shrinkage in hydrochloric acid. One is that the deformation may be caused by the electrostatic forces between the anode and the negatively charged polyions in the gel. The other relates to the screening effect of COO H + by CP which comes in from the D phase. As a large number of CP ions restrain interactions between COO H+, the gel will shrink. 

Evolution of phosphine is slow in contact with water or alkali, but explosively violent in contact with dilute mineral acids [1], However, reports of violent interaction with concentrated or dilute hydrochloric acid, and of explosive reaction with 1 1 aqua regia, have been questioned [2],... 

Alguacil, F. J. Cobo, A. Coedo, A. G. Dorado, M. T. Sastre, A. Extraction of platinum(TV) from hydrochloric acid solutions by amine alamine 304 in xylene. Estimation of the interaction coefficient between PtCl62- and H+. Hydrometallurgy 1997, 44, 203-212. 

Theory Chlorinated lime reacts with acetic acid to produce a mole each of calcium acetate, hydrochloric acid and hydrochlorous acid. The two acids interact to give water and chlorine, and the latter reacts with HI to liberate iodine that can be estimated by titrating with 0.1 N sodium thiosulphate solution. The various reactions involved may be expressed as given below ... 

Nitrous acid is formed by the interaction of sodium nitrite and hydrochloric acid as follows ... 

The contents of the nucleic acid bases in the poly-L-lysine derivatives were determined by UV spectra of the polymers after hydrolysis The polymers were hydrolyzed in 6 N-hydrochloric acid at 105°C for 24 hr, into lysine dihydrochloride and the carboxyethyl derivatives of the nucleic acid bases. The quantitative calculation was made relative to the standard sample of the carboxyethyl derivative of the nucleic acid bases. The analytical data are listed in Table 1. It was found that the thymine and uracil derivatives was completely substituted to polylysine. Low value in case of adenine base in the polymer may be attributed to the unstability of the activated ester, Ade-PNP (2), and may also be explained in terms of the steric interaction among bulky pendant groups of the polymer. When the poly-L-lysine containing about 50 mol % adenine units was again treated with Ade-PNP, the adenine unit content in the polymer increased up to 74 mol %(,] ). 

The experimental procedure can be varied by the use of reagents which will give biguanides in situ and thus form the required triazine. Examples include 493, 554) the interaction of arylamines (e.g. p-chloro-aniline hydrochloride) and cyanoguanidine, followed by acetone and hydrochloric acid. Acetone may be replaced by its bisulphite compound, by diethyl acetal or by isopropenyl acetate, but p-chlorophenylbiguanide fails to condense 113) with acetone diethyl acetal at 130°. Under the correct acid conditions, the isomeric p-chloroanilino-triazine (CXXV) is not formed on the other hand, the free p-chlorophenylbiguanide base did not react with acetone in the absence of a catalyst. 

Amitriptyline Amitriptyline, 5-(3-dimethylaminopropyliden)-10,ll-dihydrodibenzocy-cloheptene (7.1.4), differs from imipramine in that the nitrogen atom in the central part of the tricyclic system is replaced by a carbon, which is bound to a side chain by a double bond. Amitriptyline (7.1.4) is synthesized by interaction of 10,ll-dihydro-A,iV-dimethyl-57f-dibenzo[a,d]cyclohepten-5-one with 3-dimethylaminopropyhnagnesium bromide and the subsequent dehydration of the resulting tertiary alcohol (7.1.3) using hydrochloric acid [ 11]. 

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