Human future developments

The case study described here concerns a human factors audit of a computer controlled process system which was being introduced in a distillation imit of a chemical plant. The unit was in transition from replacing its pneumatic panel instrumentation with the new system. However, control had not yet been transferred and the staff were still using the panel instrumentation. The role of the project was to evaluate a preliminary design of the computer-based display system and provide recommendations for future development. 

RESEARCH ON EMOTIONS AND FUTURE DEVELOPMENTS IN HUMAN ETHOLOGY... 

Research on Emotions and Future Developments in Human Ethology... 

FDA) for use in humans to treat malaria because this drug is considered a safe drug with few side effects.These features prompted various scientists around the world to evaluate the potential of artemisinin (1) and derivatives to control cancer cells proliferation. This chapter reviews the recent advances on analytical methods for extraction and quantification of artemisinin (1) from A. annua. Examples of artemisinin-derivatives with antiproliferative activities are listed, describing the structure-activity relationships of 96 compounds. This knowledge is essential for future development and use of artemisinin derivatives in cancer therapy. The mechanism of action of artemisinin and derivatives on cancer cells have been well reviewed in literature and therefore is not discussed in this chapter. 

Taking into account its much smaller size, the agrochemical industry has been more innovative than its pharmaceutical counterpart. Ten to twelve NMEs have been launched by the agrochemical industry each year during the past 25 years. The future development of demand for agrochemicals will depend primarily on the fate of genetically modified crops. The question as to whether they will be generally accepted for human nutrition by the public... 

In 1996, about 10 years after the introduction of the first recombinant DNA product for human use, the FDA modified and streamlined the approval process for biotechnology products considered to be well characterized. These modifications, in essence, established the direction of how biologic macromolecules are researched and developed today in biotechnology-based and traditional pharmaceutical companies [2]. Well-characterized biotechnology products include (1) synthetic peptides consisting of fewer than 20 amino acids, (2) monoclonal antibodies and derivatives, and (3) recombinant DNA-derived products. Anticipating future developments, the FDA is also prepared to consider DNA plasmid products as well-characterized when the first medicinal in this class is submitted for approval. CBER now approves well-characterized biopharmaceuticals under the BLA process [3]. 

Statistics indicate that in late 1978, the American Red Cross reported a demand for thawed, deglycerolized human red cells of nearly 100,000 units per year, By May 1983, the demand was only approximately 42,000 units. Thus, it now appears that the need for frozen red cells was mainly found in filling rare donor blood types. Chaplin summarizes—future developments may yetprove previously frozen red cells to be the sleeping giant ofred-cell replacement therapy for the present, we must be content with the minor but crucial role in which they have proved their worth beyond doubt. 

In practice, further important aspects of BC are the focus of interest, concerning cooling of overtaxed muscles and particularly wound treatment of animals such as horses, sheep, cows, cats, and dogs. Extremely highly infected wounds are frequent in dogs after car crashes or similar accidents [143]. Furthermore, treatment of badly healing and permanent wounds, e.g., ulcers, and in the clinical and home-care sector both for human and veterinary medicine, as well as specific applications in tissue engineering will be major future developments. 

Finally, in an overview of important future developments, the need for empirical research into the assumptions of near miss reporting is stressed. A promising new theoretical field is that of modelling the human contribution to... 

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