Homatropine

Donnazyme 20/100 nyltoloxamine pancreatin/pepsin/homatropine/hyoscyamine/atropin Robins... [Pg.313]

Phenylglycollyltropeine Mandelyltropeine, homatropine), CigHjiOjN. This is largely used as a substitute for atropine. It crystallises in prisms, m.p. 95-5-98-5°. The hydrobromide, the salt usually employed in medicine, is a crystalline powder, m.p. 217-8° (dec.) the hydrochloride, m.p. 224-5°, and the salicylate are also used. All tl ee are freely soluble in water. The methobromide has m.p. 192-6°. The aurichloride, B. HAUCI4, forms prisms and is sparingly soluble in water. Homatropine, unlike atropine, does not give the Vitali colour reaction (p. 70). Its mydriatic effect is more rapid and transient than that of atropine. [Pg.74]

Mandelyl-ip-tropeine ( 4-homatropine), C gHaiOaN, is a thick uncrystallisable oil. Tropyl-iji-tropeine, 7112303, crystallises in colourless needles, m.p. 86°. [Pg.101]

Homatropine (mandelyltropine) being a useful mydriatic it is surprising that of nine esters of mandelic acid tried, none showed mydriatic activity though three were local anaesthetics, two of them being described as good. Only one of the tropic acid esters tried showed local anaesthetic action and that was poor. ... [Pg.109]

Cushny has compared the action of d- and Z-hyoscyamines with that of atropine, and of d-homatropine with that of dZ-homatropine in antagonising the action of pilocarpine, and finds that the order of activity of the first three is in the ratio 1 40 20, and of the second two in the ratio 4 2-5. He drew attention also to the important influence of the acyl radical in the tropeines, which exercises the maximum effect when it is a hydroxyalkyl aromatic residue and is laevorotatory and in illustration of this point gives the following table of relative activities on the basis of capacity to antagnonise pilocarpine in the salivary fistula dog —... [Pg.110]

Holarrhena spp., alkaloids, 742 pharmacological action, 748 Holarrhenine holarrhine, 743, 747 holarrhimine, 742, 743, 747 Homatropine, 74... [Pg.793]

C5H 05 542-05-2) see Dolasetron mesilate Homatropine acetone dimethyl acetal... [Pg.2280]

CgHisNO 120-29-6) see Benzatropine Clobenztropine Deptropine Homatropine Octatropine methylbromide Tropisetron... [Pg.2452]

CjHnNO 5J2-2 -7) see Homatropine ti-opinone>2,4-dicarboxylic acid (C, HnNO,) see Homatropine "ftp-Met-Asp-Phe-NHj (CjjHi NftOfiS 1947-37-1) see Ceruletide tryptamine... [Pg.2453]

Potential oscillation was measured in the presence of cholinergic agents (acetylcholine chloride, carbamylcholine chloride, carbamyl- d-methylcholine chloride, and acetyl-/6-methylcholine chloride) and anticholinergic agents (tetramethylammonium chloride, tetra-ethylammonium chloride, succinylcholine chloride, hexamethonium chloride, scopolamine hydrobromide, atropine sulfate, homatropine hydrochloride, and tubocurarine chloride)... [Pg.714]

FIG. 18 Chemical structures of (a) acetylcholine chloride, (b) carbamylcholine chloride, (c) carba-myl-y8-methylcholine chloride, (d) acetyl-/i-methylcholine chloride, (e) tetramethylammonium chloride, (f) tetraethylamonium chloride, (g) succinylcholine chloride, (h) hexamethonium chloride, (i) scopolamine hydrobromide, 0 atropine sulfate, (k) homatropine hydrochloride, and (1) tubocurar-ine chloride. [Pg.716]

HOMATROPINE HYDROBROMIDE OPHTHALMIC SOLUTION USP 5% 15ML BOTTLE 6505006895532 BT 4.39 ... [Pg.409]

Holograms, silver and, 22 639, 657-658 Holographic applications, spectrally sensitized materials for, 9 519 Holographic interferometry, 19 588-589 Holography, optical, 27 421 Holst, Axel, 25 747 Homatropine hydrobromide, 4 360t Homatropine methylbromide, 4 360t Home desalinators, 26 55 Home scrap, 23 261, 262 Home water softeners, 22 818-819 Homobenzoate esters, aroma chemicals, 3 257... [Pg.441]

Early synthetic spasmolytics resembled atropine closely, e.g. homatropine (the ester of mandelic acid and tropine (IV)). It may be noted that acetylcholine itself is an ester of a quaternary aminoalcohol and a short-chain organic acid. If the length of the chain is increased, acetylcholine activity decreases and com-... [Pg.53]

Repeated doses of atropine or homatropine are required to maintain relaxation of the pupil. Although congestive symptoms are thereby relieved, the writer has repeatedly noted paralysis of accommodation with resultant blurred vision. In short, in spite of the instillation of a mydriatic, one s vision is still impaired as the pupil is now usually dilated. [Pg.82]

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