2- Hexanone dimethyl acetal

Substituted acetylenes afford ketals.203,204 Reaction of butylacetylene (1-hexyne) with methanol gives 2-hexanone dimethyl acetal in 70% yield ... 

Acetals are formed by the action of acetylene with alcohols in the presence of a catalyst consisting of boron trifluoride and mercuric oxide. The method has been extended to the condensation of substituted acetylenes, RC s CH, with alcohols to give ketals, as illustrated by the preparation of 2-hexanone dimethyl ketal (70%). The acidic catalyst must be carefully neutralized with powdered anhydrous potassium carbonate before contacting the acetal or ketal with water. 

Acetone, acetic acid (glacial), lower alcohols, alcohol/ diethyl ether, amyl acetate, M-butyl acetate, butyl lactate, 7-butyrolactin, cyclopentanone, diethyl acetate, diethyl ketone, N,N-dimethylacetamide, dimethyl carbonate, dimethyl cyanamide, dimethylformamide, dimethyl maleate, dimethylsulfoxide, 2-ethoxyethyl acetate, ethyl acetate, ethyl amyl ketone, ethylene glycol ethers, ethyl lactate, 2-hexanone, methyl acetate, methyl ethyl ketone, methyl propyl ketone, M-methylpyrrolidone-2, 2-octanone, 1-pentanone, M-pentyl acetate, pyridine ... 

Dimethyl phthalate 1,4-Dioxane Dipropylene glycol dimethyl ether Dipropylene glycol ethyl ether Erucamide Ethoxydiglycol Ethoxyethanol acetate Ethyl acetate 2-Ethyl-1-butanol Ethyl chloride Ethylene carbonate Ethylene chlorohydrin Ethylene glycol diacetate Ethylene glycol isopropyl ether Ethylene glycol propyl ether 2-Ethyl hexanol 2-Ethyl hexyl acetate Ethyl morpholine Furan Furfuryl alcohol Heptane 4-Heptanone 2-Hexanone Isoamyl acetate Isoamyl alcohol Isobutyl acetate Isocetyl salicylate Isooctyl alcohol Isophorone 2-lsopropoxy-1-propanol Isopropyl alcohol Isopropyl ether ... 

Recordings from Staphylininae [115] include 3-methylbutanal, the corresponding alcohol, and its acetate, various ketones such as 4-methyl-3-hexanone, 4-methyl-3-heptanone, 5-methyl-3-hexanone (and the corresponding alcohol), 2-heptanone, 6-methyl-2-heptanone, 6-methyl-5-hepten-2-one as well as methyl-cyclopentene and methylfuran. In addition, the secretions of Ontholestes murinus contain the spiroacetals (2S,6R,8S)-2,8-dimethyl-l,7-dioxaspiro[5,5]-... 

Methylbutyl acetate, see sec-Amyl acetate 3-Methylbutyl acetate, see Isoamyl acetate 3-Methyl-l-butyl acetate, see Isoamyl acetate 3-Methylbutyl ethanoate, see Isoamyl acetate Methylbutyl ethyl ketone, see 5-Methyl-3-heptanone Methyl n-butyl ketone, see 2-Hexanone Methylcarbamate-l-naphthalenol, see Carbaryl Methylcarbamate-l -naphthol, see Carbaryl Methyl carbamic acid, 2,3-dihydro-2,2-dimethyl-7-... 

Probkm 28.28 Using 9-BBN plus any alkenes and unhalogenated acids or ketones, outline all steps in the synthesis of (a) 2-heptanone (b) 4-methylpentanoic acid (c) 4-methyl-2-hexanone (d) l-cyclohexyl-2-propanone (e) ethyl (trans Z-methylcyclopentyl)acetate (f) l>phenyl-4-methyM-pentanone (g) i-cyclopentyl-33 dimethyl-2-butaBone. 

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