Hepatitis B immunoglobulin

Prophylaxis of HBV can be achieved by vaccination or by passive immunity in postexposure cases with hepatitis B immunoglobulin. 

Hepatitis B immunoglobulin Human Specificity against hepatitis B surface antigen... 

Hepatitis B immunoglobulins are administered to persons who have come into contact with hepatitis B, including newborn infants whose mothers have recently been infected with the virus. 

Hepatitis B immunoglobulin (pooled plasma selected for high titres of antibodies to the virus) provides passive immunity for post-exposure prophylaxis e.g. after accidental needlestick injury. 

HBIG Hepatitis-B immunoglobulin LAP Liver active protein... 

Passive immnnization of the recipient at the time of potential exposnre to hepatitis B virus is available. Prophylactic or post-exposure administration of hepatitis B immnnoglobnlin (HBIG) is of value in the prevention of hepatitis B. Addition of anti-hepatitis-B immunoglobulin to factor concentrates appears to abolish hepatitis B virus infectivity (160,161). Hepatitis B immunization has been used effectively in controlled trials (162,163). The prophylactic effectiveness of the vaccine administered immediately after exposure to hepatitis B virus has not been established (164). 

Uniparin and many other names) is a (parenteral) ANTICOAGULANT, the sodium salt of heparin, heparitin sulphate heparan sulphate, hepatitis B immunoglobulin eglobuUn. immune, heptaminol [ban, inn] is an aminoheptanol derivative, a coronary vasodilator and carduc stimulant, formerly used to treat cardiovascular disorders. 

The two types of products available for prevention of hepatitis B infection include hepatitis B vaccine (provides long-lasting active immunity) and hepatitis B immunoglobulin (HBIg provides temporary passive immunity). The vaccine is used in preexposure prophylaxis. It is also used in postexposure prophylaxis in combination with HBIg. Vaccination is the most effective method for preventing hepatitis B (Tables 40-6, 40-7, 40-8, and 40-9). ... 

HBIg, hepatitis B immunoglobulin HBsAg hepatitis B surface antigen. From Centers for Disease Control and Prevention. Protection against viral hepatitis Recommendations of the Immunization Practices Advisory Committee (ACIP). Morb Mortal Wkly Rep 1 990 39 1-26 Centers for Disease Control and Prevention. 

Adequate anti-HBs is >10 milli-international units per milliliter by radioimmunoassay or enzyme immunoassay. anti-HBs, antibody to HBsAg HBIg, hepatitis B immunoglobulin HBsAg, hepatitis B surface antigen. 

Liver transplantation was considered as an ultimate choice for the patients with HCC, but this is problematic for patients with chronic viral hepatitis B, since the new liver is reinfected (selected reviews, 219-221). Therefore, liver transplantation should only be considered in a clinical setting wherein prevention of reinfection of the allograft is attempted (222). The use of hepatitis B immunoglobulin in high doses for prolonged periods delays rather than prevents recurrence (219). 

All healthcare personnel with potential exposure to blood, blood-contaminated body fluids, other body fluids, or sharps should receive a vaccination. Administer the hepatitis B vaccine using the intramuscular route in the deltoid muscle. The OSHA Bloodbome Pathogens standard requires employers to offer the hepatitis B vaccine free of charge to all potentially exposed employees within 10 days of hire. Administer post-exposure prophylaxis with hepatitis B immunoglobulin (passive immunization) and/or vaccine (active immunization) when indicated after per-cutaneous or mucous membrane exposure to blood known or suspected to contain hepatitis B. Needle-stick or other percutaneous exposures of unvaccinated persons should lead to initiation of the hepatitis B vaccine series. HBV vaccination requirements are as follows ... 

---