Preexposure prophylaxis

Tsai C-C, Follis KE, Sabo A, Grant RF, Bartz C, Nolte RE, Benveniste RE, Bischofberger N. Preexposure prophylaxis with 9-(2-phosphonylmethoxy-ethyl)adenine against simian immunodeficiency virus infection in macaques. J Infect Dis 1994 169 260-266. [Pg.335]

Preexposure prophylaxis 0.02 mL/kg IM for anticipated risk of <3 months, 0.06 mL/kg for anticipated risk of >3 months, repeated every 4 to 6 months for continued exposure. [Pg.436]

Rabies Inactivated virus Intramuscular (IM) Preexposure Three doses at days 0, 7, and 21 or 28 Serologic testing every 6 months to 2 years in persons at high risk 1. Preexposure prophylaxis in persons at risk for contact with rabies virus... [Pg.1407]

Hepatitis A Immune globulin (intramuscular [IM]) Preexposure prophylaxis 0.02 mL/ kg IM for anticipated risk of s 3 months, 0.06 mL/kg for anticipated risk of > 3 months, repeated every 4-6 months for continued exposure. Preexposure and postexposure hepatitis A prophylaxis. The availability of hepatitis A vaccine has greatly reduced the need for preexposure prophylaxis. [Pg.1410]

The two types of products available for prevention of hepatitis B infection include hepatitis B vaccine (provides long-lasting active immunity) and hepatitis B immunoglobulin (HBIg provides temporary passive immunity). The vaccine is used in preexposure prophylaxis. It is also used in postexposure prophylaxis in combination with HBIg. Vaccination is the most effective method for preventing hepatitis B (Tables 40-6, 40-7, 40-8, and 40-9). ... [Pg.748]

All three vaccine preparations may be administered for preexposure prophylaxis as a three-dose series of 1 mL IM on days 0 and 7 and once between days 21 and 28. Alternatively, HDCV can be administered intradermally in a dose of 0.1 mL using the same schedule. HDCV must be given using the specific intradermal dosage form and syringe. Lower rabies antibody concentrations have been observed in individuals immunized using the intradermal route while taking malaria prophylaxis concurrently. The IM route is recommended in this situation. ... [Pg.2242]

Preexposure prophylaxis does not eliminate the need for post-exposnre therapy. Persons previonsly immnnized with HDCV, RVA,... [Pg.2242]

Intramuscular vaccine should be given in the deltoid muscle in adults and in the anterolateral thigh in children. The gluteal region should not be used. The lateral aspect of the deltoid should be used for intradermal injection of HDCV when used for preexposure prophylaxis... [Pg.2242]

Stoddart CA, Nault G, Galkina SA et al (2012) Preexposure prophylaxis with albumin-conjugated C34 peptide HIV-1 fusion inhibitor in SCID-hu Thy/Liv mice. Antimicrob Agents Chemother. doi 10.1128AAC.05015-ll... [Pg.161]

Hepatitis B vaccine (20 meg IM followed by a second dose of 20 meg IM 30 days later) is used in immunization against infection from all known subtypes of hepatitis B primary preexposure prophylaxis against hepatitis B or... [Pg.321]

A) Rabies immune globulin is recommended only in patients who demonstrate an antibody response from preexposure prophylaxis... [Pg.540]

Rabies immune globulin should be given as soon as possible after exposure and must be combined with immunization using human diploid cell-derived rabies vaccine. Passive immunization is not recommended for individuals with demonstrated antibody response to preexposure prophylaxis with rabies vaccine. The answer is (A). [Pg.541]

Vaccinia vaccine remains the preeminent countermeasure for preexposure prophylaxis against smallpox. Vaccinia vaccination, vaccinia immune globulin, and methisazone each possess some efficacy in postexposure prophylaxis. [Pg.553]

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