Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Hemoglobin, oxygen dissociation curve

A 72-year-old woman with emphysema presents to the emergency room with fatigue and respiratory distress. Which set of arterial blood gas values below would represent her condition and reflect a shift of the hemoglobin oxygen dissociation curve to the right ... [Pg.119]

THE OXYGEN DISSOCIATION CURVES FOR MYOGLOBIN HEMOGLOBIN SUIT THEIR PHYSIOLOGIC ROLES... [Pg.41]

I. A 10-month-old child is being evaluated for the underlying cause of a hemolytic anemia. In the diagram shown below, the oxygen dissociation curve for hemoglobin in his erythrocytes is compared with the curve obtained with normal red cells. [Pg.177]

Hyperbolic shape of the enzyme kinetics curve Most enzymes show Michaelis-Menten kinetics (see p. 58), in which the plot of initial reaction velocity, v0, against substrate concentration [S], is hyperbolic (similar in shape to that of the oxygen-dissociation curve of myoglobin, see p. 29). In contrast, allosteric enzymes frequently show a sigmoidal curve (see p. 62) that is similar in shape to the oxygen-dissociation curve of hemoglobin (see p. 29). [Pg.57]

Figure 7.11 shows the oxygen dissociation curve of one such hemoglobin, Hb Rainier, where it is seen that this hemoglobin is still 50% saturated with oxygen at a p02 of about 12 mm Hg compared to 27 mm Hg in normal hemoglobin. The value of n in the Hill equation is 1.5 for this hemoglobin. [Pg.171]

Figure 2-4. Oxygen dissociation curve for adult hemoglobin (HbA) demonstrating the characteristics of allosteric positive comparativity. Right shift of the curve caused by het-erotrophic ligands and increased temperature leads to decreased oxygen affinity. Figure 2-4. Oxygen dissociation curve for adult hemoglobin (HbA) demonstrating the characteristics of allosteric positive comparativity. Right shift of the curve caused by het-erotrophic ligands and increased temperature leads to decreased oxygen affinity.
Early this century, A.V. Hill derived a useful equation that describes the oxygen dissociation curve of hemoglobin fairly accurately. It is... [Pg.151]

The observation by Chanutin and collaborators (CIO, S64) and by Benesch and Benesch (B25, B26) that 2,3-DPG (and also ATP and inositol hexaphosphate, or IHP) binds to hemoglobin resulting in a shift to the right of the oxygen dissociation curve has led to numerous reports which describe topics related to biochemical and medical aspects of the... [Pg.159]

Ascorbic acid appears to be toxic to certain tumor tissues however, it may increase the biological effectiveness of red blood cells by increasing the level of 2,3-diphosphoglycerate (30,31), 2,3-Diphosphoglycerate is essential to maintaining the normal oxygen dissociation curve of hemoglobin. This increase has been shown in vitro (30) and in vivo, in human subjects (31). [Pg.372]


See other pages where Hemoglobin, oxygen dissociation curve is mentioned: [Pg.335]    [Pg.1296]    [Pg.44]    [Pg.419]    [Pg.419]    [Pg.71]    [Pg.335]    [Pg.1296]    [Pg.44]    [Pg.419]    [Pg.419]    [Pg.71]    [Pg.34]    [Pg.334]    [Pg.363]    [Pg.28]    [Pg.29]    [Pg.29]    [Pg.30]    [Pg.30]    [Pg.31]    [Pg.39]    [Pg.40]    [Pg.41]    [Pg.42]    [Pg.66]    [Pg.291]    [Pg.36]    [Pg.39]    [Pg.39]    [Pg.154]    [Pg.23]    [Pg.119]    [Pg.156]    [Pg.210]    [Pg.326]    [Pg.327]    [Pg.136]    [Pg.463]    [Pg.1170]    [Pg.389]    [Pg.649]    [Pg.649]   
See also in sourсe #XX -- [ Pg.39 ]

See also in sourсe #XX -- [ Pg.150 ]

See also in sourсe #XX -- [ Pg.306 ]




SEARCH



Dissociation curves

Hemoglobin curve

Hemoglobin dissociation

Hemoglobin oxygenation

Oxygen dissociation

Oxygen dissociation curve

Oxygen dissociation curve of hemoglobin

Oxygen hemoglobin

© 2024 chempedia.info