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HEK293 kidney cell

Convolutamines I (95) and J (96) exhibited activity against parasite Trypanosoma brucei brucei with the IC50 values of 1.1 and 13.7 pM, respectively. Convolutamine I (95) also exhibited cytotoxic activity with the IC50 value of 22.0 uM against human embryonic kidney cell line, HEK293 [49]. [Pg.90]

Liposomes and lipoplexes are usually self-assembling, easy to prepare and biodegradable. They allow increased uptake of naked DNA and DNA NPs. They can also be combined with polycations to form lipid-DNA NPs. Caracciola et al. [8] observed that lipid-protamine-DNA (LPD) NPs were more efficient than lipoplexes for gene delivery in CHO (Chinese hamster ovary cells), HEK293 (human embryonic kidney cells), NIH 3T3 (mouse embryraial cells) and A17 (murine cancer cells) cells. Unfortunately, cationic liposomes exhibit significant variability in gene delivery efficiency and are often toxic to cells. [Pg.55]

Thermally hydrosilylated Human embryonic kidney cell line (HEK293) Fibronectin covalently bound to the surface allowed for cell adhesion in the absence of serum. Sinface with no boimd protein showed low cell attachment Sweetman etal. (2011)... [Pg.27]

Encapsulated into polycaprolactone (PCL) Human embryonic kidney cells (HEK293) Cells remained viable when cultured with the PCL sponge Coffer et al. (2005)... [Pg.27]

Recent results that examined the effect of pyrethroids on voltage-gated sodium channels expressed in human embryonic kidney (HEK293) cells grown in... [Pg.57]

He B, Soderlund DM (2010) Human embryonic kidney (HEK293) cells express endogenous voltage-gated sodium currents and Nav1.7 sodium channels. Neurosci Lett 469 268-272... [Pg.70]

HEK293 cells Human embryonic kidney 293 cells... [Pg.93]

Evaluation of Cardiovascular Function Using Cloned hERG Channels Expressed in Human Embryonic Kidney (HEK293) Cells... [Pg.890]

HEK293 cells from Homo sapien embryonic kidney epithelial cell line transformed with adenovirus 5 DNA and maintained in cell culture incubators In vitro... [Pg.891]

HEK293 cells are perfectly used to express and study liver specific uptake transporters like organic anion transporting polypeptides (OATPs). One should consider the endogenous expression of OATs if using HEK293 cells for the kidney specific uptake transporter. In these cases transfection of CHO (Chinese hamster ovarian) cells might be preferred. [Pg.533]

Identification of OATP1B/3 substrates is usually performed in stable OATP1B1- or OATPlB3-overexpressing systems, such as Chinese Hamster Ovary (CHO) and Human Embryonic Kidney 293 (HEK293) cells, X. Laevis oocytes, and recombinant virus [80, 82], The criterion for test compounds to be considered as... [Pg.103]

Cummins We think that the slowly repriming current is generated by PNl. In human embryonic kidney (HEK293) cells PNl does have very slow re-priming. The small neurons aren t that excitable, so you don t see the repetitive firing that is seen in a cerebellar neuron. [Pg.55]

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