Headache chronic

Exposure to carbon monoxide resulting from inadequate ventilation and/or leakage of combustion products may cause headaches, chronic tiredness or muscular weakness. High concentrations or long-term exposure may be fatal. Normal resuscitation methods and medical advice should be sought for those suffering from these effects. 

While rDNA techniques offer exciting possibilities, there are many unanswered questions about the potential toxicity that each new product represents. For example, acute clinical toxicities of interferons (IFNs) include flu-like syndrome, fever, chills, malaise, anorexia, fatigue, and headache. Chronic dose-limiting toxicities include neutropenia, thrombocytopenia, impairment of myeloid maturation, reversible dose-related hepatotoxicity, some neurological toxicity (stupor, psychosis, peripheral neuropathy) and gastrointestinal toxicity. Some of these toxicities would be difficult to ascertain in rodents, and, in fact, may be species-specific. 

HUMAN HEALTH RISKS EPA RfD 0.08 mg/kg/d Acute Risks destructive to mucous membranes, upper respiratory tract, eyes and skin burning sensation coughing wheezing laryngitis shortness of breath headache Chronic Risks no information on effects on humans. 

HUMAN HEALTH RISKS Acute Risks irritation of eyes, mucous membranes and upper respiratory tract severe skin burns depression of central nervous system weeping and twitching of eyelids headaches Chronic Risks disturbances of liver functions may cause cancer may cause genetic damage pulmonary edema more susceptible to illness. 

Attention disturbances Irritability Depression Chronic headache Chronic fatigue... 

Workers who produce or use lead should be aware of possible ha2ards. Symptoms of chronic lead poisoning include fatigue, headache, constipation, uneasy stomach, irritabiHty, poor appetite, metallic taste, weight loss, and loss of sleep. Most of these same symptoms also occur in many common illnesses, such as the flu, thus a physician must rely on tests, such as blood lead analysis, to determine chronic lead poisoning. 

Toxicology. The acute oral and dermal toxicity of naphthalene is low with LD q values for rats from 1780—2500 mg/kg orally (41) and greater than 2000 mg/kg dermally. The inhalation of naphthalene vapors may cause headache, nausea, confusion, and profuse perspiration, and if exposure is severe, vomiting, optic neuritis, and hematuria may occur (28). Chronic exposure studies conducted by the NTP ia mice for two years showed that naphthalene caused irritation to the nasal passages, but no other overt toxicity was noted. Rabbits that received 1—2 g/d of naphthalene either orally or hypodermically developed changes ia the lens of the eye after a few days, foUowed by definite opacity of the lens after several days (41). Rare cases of such corneal epithelium damage ia humans have been reported (28). Naphthalene can be irritating to the skin, and hypersensitivity does occur. 

Uses. Aspirin has analgesic, antiinflammatory, and antipyretic activity. It is used for the reHef of less severe types of pain, such as headache, neuritis, acute and chronic rheumatoid arthritis, and toothache. Aspirin can be purchased in a variety of OTC and prescription dosage forms made and formulated by many companies. Tablets, ie, buffered, plain, or enteric-coated, are the most familiar in the United States, but other forms such as powder and effervescent formulations are of considerable importance in other parts of the world. 

Nifedipine (Table 3) is a potent vasodilator that selectively dilates resistance vessels and has fewer effects on venous vessels. It does not cause reflex tachycardia during chronic therapy. Nifedipine is one of the first-line choices for black or elderly patients and patients having concomitant angina pectoris, diabetes, or peripheral vascular diseases. Nifedipine, sublingually, is also suitable for the treatment of hypertensive emergencies. Nifedipine does not impair sexual function or worsen blood Hpid profile. The side effects are flushing, headache, and dizziness. 

In cases which recover from the pulmonary edema, there is usually no permanent disability, but pneumonia may develop later. Concns of 100—150ppm are dangerous for short exposures of 30 to 60 minutes. Concns of 200—700ppm may be fatal after even very short exposures Continued exposure to low concns of the fumes, insufficient to cause pulmonary edema, is said to result in chronic irritation of the respiratory tract, with cough, headache, loss of appetite, dyspepsia, corrosion of the teeth and gradual loss of strength... 

The exact cause of chronic pain of a nonmalignant nature may or may not be known. This type of pain includes the pain associated with various neuropathic and musculoskeletal disorders such as headaches, fibromyalgia, rheumatoid arthritis, and osteoarthritis. 

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