Harvard

R. Gomer, Field Emission and Field Ionization, Harvard University Press, Cambridge, MA, 1961. 

Kuhn T S 1957 The Copernican Revoiution Pianetary Astronomy in the Deveiopment of Western Thought (Cambridge, MA Harvard University Press)... 

Figure Bl.4.4. (a) An outline of the Harvard University eleetrie diseharge siipersonie nozzle/Foiirier transfonn mierowave speetroineter. (b) The rotational states of HCj N observed with this apparatus [31],...

Brooks H, Birch F, Hoiton G and Paui W (eds) 1964 Collected Experimental Papers of PW Bridgman voi i-Vii (Cambridge Harvard University Press)... 

Eric J. Heller, Department of Chemistry, Harvard-Smithsonian Center for Astrophysics, Cambridge, Massachusetts, U.S.A. 

In 1967, work was presented from a Sheffield group on indexing chemical reactions for database budding. In 1969, a Harvard group presented its first steps in the development of a system for computer-assisted synthesis design. Soon afterwards, groups at Brandeis University and TU Munich, Germany, presented their work in this area. 

The use of computers for the design of chemical syntheses was first demonstrated by Corey and Wipke in 1969 with their program OCCS [30]. The successor to OCCS, LHASA [31], is generally considered to be the first synthon-based system. Its development is still going on. Currently, three groups are working on LHASA, one at Harvard University, USA [32], one at the University of Leeds, UK [33], and... 

P2] LHASA Group homepage, http //lhasa.harvard.edu/... 

Wofe." rh c BIO + force field is an im plern en lation oflheCH. ARMM (Chcmistry at H.ARvard MacromoIceular Mechanics ) force field developed in the group of Martin Karplusat Harvard University, l.ike. AMBER and OP1.S, it is primarily designed to explore rnacro-moleciilcs. 

During my subsequent stay at the Dow Eastern Research Laboratory in Boston, I regularly attended and participated in the weekly Bartlett-Westheimer seminars at Harvard. I must have made some impression,... 

Nonclassical ions, a term first used by John Roberts (an outstanding Caltech chemist and pioneer in the field), were defined by Paul Bartlett of Harvard as containing too few electrons to allow a pair for each bond i.e., they must contain delocalized (T-electrons. This is where the question stood in the early 1960s. The structure of the intermediate 2-norbornyl ion could only be suggested indirectly from rate (kinetic) data and observation of stereochemistry no direct observation or structural study was possible at the time. 

Chemistry at Harvard macromolecular mechanics (CHARMM) is the name of both a force field and a program incorporating that force field. The academic version of this program is designated CHARMM and the commercial version is called CHARMm. It was originally devised for proteins and nucleic acids. It has... 

CHARMM (chemistry at Harvard macromolecular mechanics) a molecular mechanics force field... 

In the last fifteen years macrolides have been the major target molecules for complex stereoselective total syntheses. This choice has been made independently by R.B. Woodward and E.J. Corey in Harvard, and has been followed by many famous fellow Americans, e.g., G. Stork, K.C. Nicolaou, S. Masamune, C.H. Heathcock, and S.L. Schreiber, to name only a few. There is also no other class of compounds which is so suitable for retrosynthetic analysis and for the application of modem synthetic reactions, such as Sharpless epoxidation, Noyori hydrogenation, and stereoselective alkylation and aldol reactions. We have chosen a classical synthesis by E.J. Corey and two recent syntheses by A.R. Chamberlin and S.L. Schreiber as examples. 

The synthetic fiber industry as we know it began m 1928 when E I Du Pont de Nemours Company lured Professor Wallace H Carothers from Harvard University to direct their research department In a few years Carothers and his associates had pro duced nylon the first synthetic fiber and neoprene a rubber substitute Synthetic fibers and elastomers are both products of important contemporary industries with an economic influence far beyond anything imaginable m the middle 1920s... 

Frontier orbital analysis is a powerful theory that aids our understanding of a great number of organic reactions Its early development is attributed to Professor Kenichi Fukui of Kyoto University Japan The application of frontier orbital methods to Diels-Alder reactions represents one part of what organic chemists refer to as the Woodward-Hoffmann rules a beautifully simple analysis of organic reactions by Professor R B Woodward of Harvard University and Professor Roald Hoffmann of Cornell University Professors Fukui and Hoffmann were corecipients of the 1981 Nobel Prize m chemistry for their work... 

Nuclear magnetic resonance of protons was first detected in 1946 by Edward Purcell (Harvard) and by Felix Bloch (Stanford) Purcell and Bloch shared the 1952 Nobel Prize in physics... 

The dependence of on dihedral angle is re ferred to as the Karplus relationship after Martin Karplus (Harvard University) who offered the presently accepted theoretical treat ment of it... 

The task of relating carbohydrate configurations to names requires either a world class memory or an easily recalled mnemonic A mnemonic that serves us well here was pop ularized by the husband-wife team of Lours F Fieser and Mary Fieser of Harvard Uni versity m their 1956 textbook Organic Chemistry As with many mnemonics it s not clear who actually invented it and references to this particular one appeared m the chem ical education literature before publication of the Fiesers text The mnemonic has two features (1) a system for setting down all the stereoisomeric d aldohexoses m a logical order and (2) a way to assign the correct name to each one... 

Animals accumulate cholesterol from then diet but are also able to biosynthesize It from acetate The pioneering work that identified the key intermediates m the com plicated pathway of cholesterol biosynthesis was carried out by Konrad Bloch (Harvard) and Feodor Lynen (Munich) corecipients of the 1964 Nobel Prize for physiology or... 

Roots-Bernstein, R. S. Discovering. Harvard University Press Cambridge, MA, 1989. 

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