Compounds halogenated

INTER HALOGEN COMPOUNDS AND POLYHALIDES There are four types of interhalogen compound ... 

Nitroamlines. Acetyl derivatives (p. 388), Benzoyl derivatives (p. 388). Diamines. Diacet> l derivatives (p. 388), Dibenzoyl derivatives (p. 388). Halogeno-hydrocarbons, a-Naphthyl ethers (from reactive halogen compounds, p. 391, and their Picratcs, p. 394), Nitro-derivatives (p.39i). Carboxylic acid (if oxidisable side chain) (p. 393). 

The method is general for all organic halogen compounds and is the standard method for almost all such compounds, except of course... 

Liquid sulphur compounds should be weighed and introduced into the Carius tube by precisely the same methods as those described for liquid halogen compounds (p. 442). 

Control experiment. This is not necessary if the sodium peroxide is known to be chlorine-free. If there is any doubt on this point, the whole operation should be repeated precisely as before, but omitting the organic halogen compound. A small thiocyanate titration value may be found, and this should be deducted from all determinations in which the above quantity of the particular batch of sodium peroxide is used. 

Table 111,42 deals with a number of aliphatic halogen compounds together with their crystalline derivatives. Some aromatic compounds, which simulate the properties of aliphatic haUdes in some respects, are included. 

The properties of a number of aromatic halogen compounds are collected in Table IV,28. 

It will be observed that halogen compounds are not listed separately, but appear in each of the seven groups in accordance with their solubility behaviour. Similarly, certain compounds containing N or S will fall in Groups I-IV (see preceding Section). 

Halogen compounds. re-Butyl bromide Chlorobenzene AUyl bromide Benzoyl chloride. 

Aliphatic Halogen Compounds, Table III, 42 Aromatic Halogen Compounds, Table IV, 28. Aliphatic Ethers, Table III, 60. 

Naphthalene hydrocarbons halogen compounds, nitrogen compounds. (1949.) hydroxy compounds. (l950.) oxo-compounds except quinones. (1950.) quinones. (1962.)... 

Table 11. Open-chain oligofunctional nitrogen and halogen compounds.

A key step in the reaction mechanism appears to be nucleophilic attack on the alkyl halide by the negatively charged copper atom but the details of the mechanism are not well understood Indeed there is probably more than one mechanism by which cuprates react with organic halogen compounds Vinyl halides and aryl halides are known to be very unreactive toward nucleophilic attack yet react with lithium dialkylcuprates... 

TABLE B Selected Physical Properties of Representative Organic Halogen Compounds... 

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