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Halides nucleophilicity

These reactions follow first-order kinetics and proceed with racemisalion if the reaction site is an optically active centre. For alkyl halides nucleophilic substitution proceeds easily primary halides favour Sn2 mechanisms and tertiary halides favour S 1 mechanisms. Aryl halides undergo nucleophilic substitution with difficulty and sometimes involve aryne intermediates. [Pg.283]

First order Rate = k[alkyl halide] (Section 8 8) Second order Rate = k[alkyl halide][nucleophile] (Section 8 3)... [Pg.356]

Section 10 10 Protonation at the terminal carbon of a conjugated diene system gives an allylic carbocation that can be captured by the halide nucleophile at either of the two sites that share the positive charge Nucleophilic attack at the carbon adjacent to the one that is protonated gives the product of direct addition (1 2 addition) Capture at the other site gives the product of conjugate addition (1 4 addition)... [Pg.417]

Kinetic studies of these reactions reveal that they follow a second order rate law Rate = [Aryl halide] [Nucleophile]... [Pg.977]

Attack by the halide nucleophile at the sp hybridized carbon of the alkyl group is anal ogous to what takes place in the cleavage of dialkyl ethers Attack at the sp hybridized carbon of the aromatic nng is much slower Indeed nucleophilic aromatic substitution does not occur at all under these conditions... [Pg.1011]

CHAPTER 11 Reactions of Alkyl Halides Nucleophilic Substitutions and Eliminations... [Pg.360]

Chapter 11, Reactions of Alkyl Halides Nucleophilic Substitutions and Eliminations—A discussion of the El cB reaction has been added to Section 11.10, and a new Section 11.11 discusses biological elimination reactions. [Pg.1337]


See other pages where Halides nucleophilicity is mentioned: [Pg.327]    [Pg.767]    [Pg.90]    [Pg.326]    [Pg.327]    [Pg.338]    [Pg.767]    [Pg.388]    [Pg.318]    [Pg.247]    [Pg.439]    [Pg.129]   
See also in sourсe #XX -- [ Pg.130 ]

See also in sourсe #XX -- [ Pg.130 ]




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Acid halide nucleophiles

Alkenyl halides nucleophilic reactions

Alkyl Halides Nucleophilic Substitution and Elimination

Alkyl Halides and Nucleophilic Substitution

Alkyl halides Compounds with halogen nucleophilic

Alkyl halides nucleophiles

Alkyl halides nucleophilic aliphatic

Alkyl halides nucleophilic substitution reactions

Alkyl halides with typical nucleophiles

Alkyl halides, from nucleophilic substitution

Alkyl halides, from nucleophilic substitution reactions

Alkyl halides, nucleophilic displacement

Alkyl halides, nucleophilic substitution

Allyl halides nucleophilic substitution

Allylic and Benzylic Halides in Nucleophilic Substitution Reactions

Allylic halides, nucleophilic substitution

Aryl halides and nucleophilic aromatic substitution

Aryl halides nucleophilic addition

Aryl halides nucleophilic aromatic substitution

Aryl halides nucleophilic coupling

Aryl halides nucleophilic reactions

Aryl halides nucleophilic substitution

Aryl halides radical nucleophilic substitution

Benzylic halides in nucleophilic substitution reactions

Benzylic halides, nucleophilic substitution

Carbon nucleophiles alkyl halides

Carbon nucleophiles allyl halides

Carbon nucleophiles vinyl halide/triflates

Carbonyl halides nucleophilicity

Cross-Coupling of Aryl Halides with Anionic C-Nucleophiles

Enzyme-Catalyzed Nucleophilic Substitutions of Alkyl Halides

Halide and Hydride Nucleophiles

Halide as a nucleophile alkyl halides

Halide ions as nucleophiles

Halide nucleophiles

Halide nucleophilicities

Halide nucleophilicities

Halides aromatic nucleophilic substitution

Halides, aryl reaction with sulfur nucleophiles

Halogens halide nucleophilicity

Heteroaryl halides, nucleophilic substitution

I Reactions of Alkyl Halides Nucleophilic Substitutions and Eliminations

Key Concepts—Alkyl Halides and Nucleophilic Substitution

Metal halide, nucleophilic alkylation

Neopentyl halides nucleophilic substitution

Nitrobenzyl halides nucleophilic substitutions

Nucleophile halide ions

Nucleophiles alkyl halide substitution reactions

Nucleophilic Aliphatic Substitution Preparation of Alkyl Halides

Nucleophilic Substitution in Benzylic Halides

Nucleophilic Substitution in Nitro-Substituted Aryl Halides

Nucleophilic Substitution of Aryl Halides, SN2Ar

Nucleophilic acyl substitution acid halides

Nucleophilic acyl substitution reaction acid halides

Nucleophilic alkyl substitution allylic halides

Nucleophilic alkyl substitution benzylic halides

Nucleophilic attack alkyl halides

Nucleophilic halide additives

Nucleophilic protic/halide additives

Nucleophilic reactions halides, lithium cuprate

Nucleophilic reactions of methyl halides

Nucleophilic substitution in alkyl halides

Nucleophilic substitution of allylic halides

Nucleophilic substitution reactions halides

Nucleophilic substitution reactions of alkyl halides

Nucleophilic substitution, aromatic activated aryl halides

Nucleophilicity of halide ions

Organic halides nucleophilic reactions

Palladium-catalyzed nucleophilic fluorination of (hetero)aryl (pseudo)halides

Phenacyl halides, nucleophilic

Phenols and Aryl Halides Nucleophilic Aromatic Substitution

Radical-nucleophilic aromatic substitution halides

Reactions of Alkyl Halides Nucleophilic Substitutions and Eliminations

Sulphonyl halides nucleophilic substitution

Vinyl halide nucleophilic vinylic substitution

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