Nucleophilic substitution, aryl halides

These reactions follow first-order kinetics and proceed with racemisalion if the reaction site is an optically active centre. For alkyl halides nucleophilic substitution proceeds easily primary halides favour Sn2 mechanisms and tertiary halides favour S 1 mechanisms. Aryl halides undergo nucleophilic substitution with difficulty and sometimes involve aryne intermediates. [Pg.283]

Aryl halides undergo substitution by certain nucleophiles by a chain mechanism of the S l class. " Many of the reactions are initiated photochemically and most have been conducted in liquid ammonia solution. [Pg.1048]

CHAPTER 21 PHENOLS AND ARYL HALIDES Nucleophilic Aromatic Substitution... [Pg.946]

A second general reaction which proceeds by an SrnI mechanistic pattern involves aryl halides. Aryl halides undergo substitution be certain nucleophiles by... [Pg.716]

PHENOLS AND ARYL HALIDES NUCLEOPHILIC AROMATIC SUBSTITUTION... [Pg.530]

See also in sourсe #XX -- [ Pg.822 , Pg.826 , Pg.827 , Pg.828 , Pg.829 , Pg.830 , Pg.831 , Pg.832 , Pg.833 , Pg.834 , Pg.835 , Pg.836 , Pg.837 , Pg.838 , Pg.839 , Pg.840 ]

See also in sourсe #XX -- [ Pg.822 , Pg.826 , Pg.827 , Pg.828 , Pg.829 , Pg.830 , Pg.831 , Pg.832 , Pg.833 , Pg.834 , Pg.835 , Pg.836 , Pg.837 , Pg.838 , Pg.839 , Pg.840 ]

See also in sourсe #XX -- [ Pg.849 ]

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