Guanine triphosphate

Singh AK. 1993. Effects of chronic low-level lead exposure on mRNA expression, ADP-ribosylation and photoaffmity labelling with [ -32P]guanine triphosphate -y -azidoanilide of GTP-binding proteins in neurons isolated from the brain of neonatal and adult rats. Biochem Pharmacol 45 1107-1114. 

Figure 1.10 Model of a G protein-coupled receptor with 7 membrane-spanning domains. Binding of an agonist to the receptor causes GDP to exchange with GTP. The a-GTP complex then dissociates from the receptor and the py complex and interacts with intercellular en mes or ion channels. The Py complex can activate an ion channel or possibly also interact with intercellular enzymes. GDP, guanine diphosphate GTP, guanine triphosphate cAMP, cyclic adenosine monophosphate PKC, protein kinase C PLC, phospholipase C DAG, diacylglycerol.

Blot overlays include the probing of membrane with various molecules to detect the presence of specific binding domains, for example, with guanine triphosphate (25,26) or proteoglycans (27). In the Southern or North Western blotting, the membrane is probed with deoxyribonucleic acid or ribonucleic acid molecules to detect nucleic-acid binding proteins (28). 

When ATP releases inorganic phosphate and reverts to ADP, a quantity of energy equivalent to 31 kJ of energy per mole of ATP is released that can be utilized metabolically. A pair of species that are similar in function to ATP and ADP are guanine triphosphate (GTP) and guanine diphosphate (GDP). 

N-ras mutation Signal transduction Guanine diphosphate (GDP)/ guanine triphosphate (GTP) binding protein Acute myeloid leukemia, neuroblastoma... 

When a neurotransmitter or hormone binds with its receptor, the a subunit of the G-protein combined with GTP (guanine triphosphate) detaches and activates an effector in the cell (see Figure 3.6). 

GTP - guanine triphosphate - transfers phosphate groups in cellular reactions GTPase - enzyme that converts GTP into GDP by removal of phosphate group HDL high-density lipoprotein - small lipoprotein circulating in blood mops up cholesterol... 

Abbreviations used in this chapter APR, ascorbate free radical Con A, concanavalin A CoQ, coenzyme Q DHA, dehydroascorbate ESR, elecron spin resonance GTP, guanine triphosphate LFA, Umax flavus agglutinin SDHA, semidehydroascorbate WGA, wheat germ agglutinin. 

Phosphates such as ATP and guanine triphosphate (GTP) are used to phosphorylate proteins. This is one of the fundamental mechanisms where chemical energy is converted into mechanical energy, since transfer of the bulky phosphate group causes proteins to change shape and thus produces mechanical effects. The effects of phosphate produce... 

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