Green chemistry patents

This manufacturing process received the Presidential Green Chemistry Challenge Award (2006) for alternative synthetic pathways, the IChemE AstraZeneca Award for excellence in green chemistry and chemical engineering (2005), and the Thomas Alva Edison Patent Award (2009) for Merck s U.S. Pat. 7,468,459. 

F., Ammermann, E., Lorentz, G., and Strathmann, S. (1999) New bi phenyl-amide derivatives are active against wide range of phytopathogenic fungi. German Patent DE19735224 (c) Rouhi, A.M. (2004) Chem. Eng. News, 82 (36), 49-58. Anastas, P.T. and Warner, J.C. (1998) Green Chemistry Theory and Practice, Oxford University Press, New York, p. 30. 

More attention should be paid to patent literature since this is essential to probe what the chemical industry has done in the area of green chemistry currently it is weakly covered in course syllabi... 

Nameroff, T. J., Garant, R. J., Albert, M. B. Adoption of green chemistry An analysis based on US patents. Research Policy, 33 959-974, 2004. 

The use of zeolites in the manufacture of cumene is of immense importance. About 7 million metric tons of cumene are produced annually worldwide. The earlier-used process involved alkylation of benzene over a solid phosphoric acid or an aluminum chloride catalyst. Cumene Production, U.S. Patent 4008290. Both catalysts are toxic in nature. The Mobil/Badger cumene process (Mobil Technology Co., 1997) uses the less toxic carozine zeolite catalyst (see Fig. 3.7). In addition, it also generates less waste and requires less energy than the earlier catalysts, thus simultaneously satisfying various conditions of green chemistry. 

A further interesting application of HBEA zeolite is illustrated by the direct benzoylation of arenes with benzoic acids. The synthetic method is the subject of a patent and shows very intoesting prop-a"ties from a green chemistry point of view [33]. As an example, a mixture of toluene, para-chloro-benzoic acid, and a HBEA previously calcined at 400°C (150mg/mmol) pressurized with rritiogen to 2x lO Pa, heated to 200°C, and stirred for 4h gives 4-chloro-4 -methylbarzophenone in 84% yield. 

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