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Graft-versus-tumor effect

O Hematopoietic cell transplantation (HCT) is a procedure used mainly to treat hematologic malignancies via high-dose chemotherapy and/or a graft-versus-tumor effect. [Pg.1447]

Graft-versus-tumor effect Cytotoxic T lymphocytes in the donor stem cells have anti-cancer activity. [Pg.1567]

Posttransplant immunotherapy is based on the graft-versus-tumor (CVT) effect caused by certain subsets of T cells responsible for eradication of malignant cells. Posttransplant immunotherapy includes the use of donor lymphocyte infusions, immunomodulatory cytokines, monoclonal antibodies, or antitumor vaccines. [Pg.2541]

Male C57BL/6 mice that were exposed to Aroclor 1016 in the diet at an estimated dose of 22 mg/kg/day for up to 40 weeks had no consistent effects on thymus and spleen weights, lymphocyte counts, or lymphocyte function as evaluated by the splenic graft-versus-host (GVH) response, mixed lymphocyte response, mitogenic response to stimulation by PHA or LPS, or cytotoxic activity of sensitized lymphocytes to target tumor cells (Silkworth and Loose 1978). [Pg.186]


See other pages where Graft-versus-tumor effect is mentioned: [Pg.1447]    [Pg.1448]    [Pg.1453]    [Pg.1453]    [Pg.61]    [Pg.166]    [Pg.536]    [Pg.1801]    [Pg.1801]    [Pg.2548]    [Pg.2555]    [Pg.180]    [Pg.185]    [Pg.186]    [Pg.1447]    [Pg.1448]    [Pg.1453]    [Pg.1453]    [Pg.61]    [Pg.166]    [Pg.536]    [Pg.1801]    [Pg.1801]    [Pg.2548]    [Pg.2555]    [Pg.180]    [Pg.185]    [Pg.186]    [Pg.1449]    [Pg.1452]    [Pg.2547]    [Pg.342]    [Pg.344]    [Pg.177]    [Pg.1228]    [Pg.746]    [Pg.219]    [Pg.599]    [Pg.756]    [Pg.106]    [Pg.158]    [Pg.2519]    [Pg.921]   
See also in sourсe #XX -- [ Pg.1448 , Pg.1452 ]




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Grafting effects

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