Gonadotropin receptors

Leucine residues 2, 5, 7, 12, 20, and 24 of the motif are invariant in both type A and type B repeats of the ribonuclease inhibitor. An examination of more than 500 tandem repeats from 68 different proteins has shown that residues 20 and 24 can be other hydrophobic residues, whereas the remaining four leucine residues are present in all repeats. On the basis of the crystal structure of the ribonuclease inhibitor and the important structural role of these leucine residues, it has been possible to construct plausible structural models of several other proteins with leucine-rich motifs, such as the extracellular domains of the thyrotropin and gonadotropin receptors. [Pg.56]

Menon, K.M.J., Clouser, C.L., and Nair, A.K. 2005. Gonadotropin receptors role of post-translational modifications and post-transcriptional regulation. Endocrine 26(3), 249-257. [Pg.327]

Indrapichate, K., Meehan, D., Lane, T. A., et al. (1992) Biological actions of monoclonal luteinizing hormone/human chorionic gonadotropin receptor antibodies. Biol. Reprod. 46, 265-278. [Pg.265]

Ovarian Steroid-Secreting Cells Steroidogenic cells within the ovary are also transient cell populations. While the development of gonadotropin receptors... [Pg.2232]

Bagavandoss P, Midgley AR Jr. 1988. Biphasic action of retinoids on gonadotropin receptor induction in rat granulosa cells in vitro. Life Sci. 43 1607-14... [Pg.195]

Gonadotropin and gonadotropin-receptor abnormalities signal defects Enzyme deficiencies cho/esfero/c/esmo/ase, 17a-hydroxylase, 17, 20-desmolase Galactosemia... [Pg.1508]

Nagayama, Y., Wadsworth, H.L., Chazenbalk, G.D., Russo, D., Seto, P. and Rapoport, B. (1991) Thyrotropin-luteinizing hormone/chorionic gonadotropin receptor extracellular domain chimeras as probes for thyrotropin receptor function. Proc. Natl Acad. Sci. USA 88 902-905. [Pg.64]

Braun, T., Schofield, P.R. and Sprengel, R. (1991) Amino-terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity. EMBO J. 10 1885-1890. [Pg.64]

Dufau, M., et al. (1973). Characteristics of a Soluble Gonadotropin Receptor from the Rat Testis, /. Biol. Chem. [Pg.92]

Wiebe, J.P., K.J. Barr, and K.D. Buckingham. 1988. Effect of prenatal and neonatal exposure to lead on gonadotropin receptors and steroidogenesis in rat ovaries. J. Toxicol. Environ. Health 24(4) 461-476. [Pg.145]

Nuttinck F, Charpigny G, Mermillod P, Loosfelt H, Meduri G, Freret S, Giimard B, Heyman Y. 2004. Expression of components of the insulin-like growth factor system and gonadotropin receptors in bovine cumulus-oocyte complexes during oocyte maturation. Domest Anim Endocrinol 27(2) 179-195. [Pg.486]

Bellisario, R., and Bahl, O. P., 1975, Human chorionic gonadotropin. V. Tissue specificity of binding and partial characterization of soluble human chorionic gonadotropin-receptor complexes, /. Biol. Chem. 250 3837. [Pg.599]

Rao, C. V., and Saxena, B. B., 1973, Gonadotropin receptors in the plasma membranes of rat luteal cells. Biochim. Biophys. Acta 313 372. [Pg.615]

Gonadotropin receptor (GR) (murine Leydig tumor ceU line) Hormone-receptor-detergent complex Triton X-100 0.76 87R2... [Pg.213]

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