Glycyrrhiza

The first paper on the bioactive polysaccharides from Glycyrrhiza uralensis roots was published in 1996 by Kiyohara et al. [57]. They isolated a pectic type polymer with anti-complementary and mitogenic activity that was an acidic pectin, possibly containing rhamnogalacturonan type I as part of the total structure. Degradation of the uronic acid part of the molecule decreased both types of bio activities. The neutral oligosaccharide chains were shown to retain some of the activities of the native polymer, but it was suggested that they should be attached to the acidic core to retain maximum activity. 

Glycyrrhiza uralensis X Bone marrow cell proliferating activity [59]... 

Pectic polysaccharide from roots of Glycyrrhiza uralensis Possible contribution of neutral oligosaccharide in the galacturonase resistant region to anti-complementary and mitogenic activities... 

OTANI, K., TAKAHASHI, T., FURUYA, T., AYABE, S., Licondione synthase, a cytochrome P450 monooxygenase catalyzing 2-hydroxylation of 5-deoxyflavanone, in cultured Glycyrrhiza enchinata L. cells, Plant Physiol., 1994,105,1427-1432. 

Source Indole was detected in jasmine flowers Jasminum officinale), licorice [Glycyrrhiza glabra), kohlrabi stems [Brassica oleraceavAT. gongylodes), and hyacinth flowers Hyacinthus orientalid at concentrations of 42 to 95, 2, 1.33, and 0.24 to 3.45 ppm, respectively. Indole also occurs in tea leaves, black locust flowers, corn leaves, petitgrain, and yellow elder (Duke, 1992). 

Licorice Glycyrrhiza glabra) Uses Expectorant, shampoo, GI complaints Action T Mucus secretions, peptic activity, i scalp sebum secretion Available forms Liq ext, bulk dried root, tea 15 g once/d PO of licorice root intake... 

The major sweet principle of licorice root (Glycyrrhiza glabra), glycyrrhizin (1) (content 4%), has been used as a sweetener and flavor enhancer in foods, tobacco products, and in medicine as an anti-inflammatory agent (Fig. 4). 

Hormonal effects. A commercial product, PC-SPES, composed of Chrysantemum morifolium, Ganoderma lucidum, Glycyrrhiza glabra, Isatis indigotica, Panax pseudoginseng, Rabdosia rubescens, Scutellaria baicalensis, and Serenoa repens was tested in hormone-insensitive cell lines LNCAP-BCL-2, PC-3, and DU-145 at variable concentrations. LNCAP, the only hormone-sensitive cell line, was affected by the lowest dose of PC-SPES tested . 

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