Glycyrrhiza, powders

Ammoniated Glycyrrhizin occurs as a brown powder. It is precipitated by acid from the water extract of dried and ground rhizomes and roots of Glycyrrhiza glabra or related Glycyrr-hiza (licorice root) (Fam. Leguminosae) and neutralized with dilute ammonia. Suitable diluents may be added. 

For amenorrhea due to blood stasis and replete heat in the interior with dry, hard stools and constipation, add Radix Et Rhizoma Rhei (Da Huang), Mirabilitum (Mang Xiao), and Radix Glycyrrhizae (Gan Cao). This results in Yu Zhu San (Jade Candle Powder). 

For headache due to wind heat with dizziness and vertigo, add Flos Chrysanthemi Morifolii Ju Hua), Bombyx Batryticatus Jiang Can), and mix-fried Radix Glycyrrhizae Zhi Gan Cao). This results in Ju Hua Cha Tiao San (Chrysanthemum Tea Regulating Powder). 

Komiyama, BC, Y. Kawakubo, T. Fukushima, et al. 1977. Acute and subacute toxicity test on the extract from Glycyrrhiza. Oyo Yakuri 14(4) 535-548. Cited in Isbrucker, R.A., and G.A. Burdock. 2006. Risk and safety assessment on the consumption of Licorice root (Glycyrrhiza sp.), its extract and powder as a food ingredient, with emphasis on the pharmacology and toxicology of glycyr-rhizin. Regul. Toxicol. Pharmacol. 46(3) 167-192. 

Definition Obtained by extraction from ammoniated glycyrrhizin, derived from roots of Glycyrrhiza glabra Empirical C42H65NO16 5H2O Properties Wh. powder sweet taste sol. in ammonia insol. in glacial acetic acid m.w. 839.91... 

C22H24O6 M 384.428 Constit. of the roots of Glycyrrhiza uralensis (Leguminosae). Amorph. powder, [a] 9 (c, 0.01 in MeOH). 

Weinberg, D.S., Manier, M.L., Richardson, M.D., and Haibach, F.G., Identification and quantification of anticarcinogens in garlic extract and licorice [Glycyrrhiza rp.] root extract powder, J. High Resol. Chromatogr., 15, 641 54, 1992. 

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