Glycosylphosphatidylinositol-anchored proteins

Antony, A. C., and Miller, M. E. (1994). Statistical prediction of the locus of endoproteo-lytic cleavage of the nascent polypeptide in glycosylphosphatidylinositol-anchored proteins. Biochem. J. 298, 9-16. 

Watanabe, R., Funato, K., Venkataraman, K., Futerman, A. H., and Riezman, H. (2002). Sphingolipids are required for the stable membrane association of glycosylphosphatidylinositol-anchored proteins in yeast. J. Biol. Chem. 277(51), 49538—49544. 

Gillmor, C. S., Lukowitz, W., Brininstool, G., Sedbrook, J. C., Hamann, T., et al., Glycosylphosphatidylinositol-anchored proteins are required for cell wall synthesis and morphogenesis in arabidopsis. Plant Cell 2005, 17 (4), 1128-1140. 

Low, M.G., 2000, Glycosylphosphatidylinositol-anchored proteins and their phospholipases. In Cockcroft, S. (ed.), Frontiers in Molecular Biology, Vol. 27, Biology of Phosphoinositides. Oxford University Press, New York, pp. 211-238. 

Sharom, F.J., and Lehto, M.T., 2002, Glycosylphosphatidylinositol-anchored proteins Structure, function, and cleavage by phosphatidylinositol-specific phospholipase C. Biochem. Cell. Biol. 80 535-549. 

Examples of receptors and ligands involved in RME. Specific gene symbols of representative human receptor and ligand proteins are listed in parentheses. TM transmembrane protein GPI glycosylphosphatidylinositol anchored protein 7TM Seven-transmembrane protein. 

Peyron P, Bordier C, N Diaye EN et al. Nonopsonic phagocytosis of Mycobacterium kansasii by human neutrophils depends on cholesterol and is mediated by CR3 associated with glycosylphosphatidylinositol-anchored proteins.) Immunol 2000 165(9) 5186-5191. 

In the plasma membrane, GSLs are believed to segregate into microdomains that are also enriched in glycosylphosphatidylinositol-anchored proteins, sphingomyelin, and cholesterol [12]. Because of their specific localization on the plasma membrane, especially in... 

Schroeder RJ, Ahmed SN, Zhu Y, London E, Brown DA. Cholesterol and sphingolipid enhance the Triton X-100 insolubility of glycosylphosphatidylinositol-anchored proteins by promoting the formation of detergent-insoluble ordered membrane domains. J Biol Chem 1998 273 1150-1157. 

Atomic force microscopy reveais sphyingomyeiin rafts (orange) protruding from a dioieoyiphosphatidylcholine background (biack) in a mica-supported iipid bilayer. Placental alkaline phosphatase (yellow peaks), a glycosylphosphatidylinositol-anchored protein, is shown to be almost exclusively raft associated. [From D. E. Saslowsky etal., 2002, J. Biot. Chem. 277 26966-26970.1... 

Mammalian PLDs are now the subject of intense interest as they appear to be intimately involved in signal transduction (M. McDermott, 2004 G.M. Jenkins, 2005). Two mammalian PLDs have been identified and these contain several domains often associated with signal transduction proteins including a PH domain and a separate phosphatidylinositol-bis-phosphate-binding domain. PLC and PLD that act on glycosylphosphatidylinositol-anchored proteins on the cell surface are of growing importance and are discussed in Chapter 2. 

Walton, K. A., Hsieh, X., Gharavi, N., Wang, S., Wang, G., Yeh, M., Cole, A. L., and Berliner, J. A. 2003b. Receptors involved in the oxidized l-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine-mediated synthesis of interleukin-8. A role for Toll-like receptor 4 and a glycosylphosphatidylinositol-anchored protein. 278, 29661-6. 

Berliner, J. A., Receptors involved in the oxidized l-palmitoyl-2-arachidonoyl-sw-glycero-3-phosphorylcholine-mediated synthesis of interleukin-8. A role for Toll-like receptor 4 and a glycosylphosphatidylinositol-anchored protein, 2003,... 

Yoshitake, H., Takeda, Y., Nitto, T., Sendo, F., and Araki, Y., 2003. GPI-80, a (32 integrin associated glycosylphosphatidylinositol-anchored protein, concentrates on pseudopodia without association with (32 integrin during neutrophil migration. Immunobiology. 208 391-399. 

Ko, Y.-G., and Thompson, G. A., Jr. (1995) Purification of glycosylphosphatidylinositol-anchored proteins by modified Triton X-114 partitioning and preparative gel electrophoresis. Anal. Biochem. 224,166-172. 

Testicular angiotensin-converting enzyme with different glycan modification characterization on glycosylphosphatidylinositol-anchored protein releasing and dipeptidase activities (2009) Kondoh et al. [56]... 

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