Glucose transporter function

M. A. Kasanidd and E E Pilch, Regulation of glucose transporter function, Diab. Care. 13 219-227 (1990). 

Burchmore RJS, Rodriguez-Contreras D, McBride K et al. Genetic characterization of glucose transporter function in Leishmania mexicana. Proc Natl Acad Sd USA 2003 100(7) 3901-3906. 

Scheepers A, Joost HG, Schurmann A (2004) The glucose transporter families SGLT and GLUT molecular basis of normal and aberrant function. JPEN J Parenter Enteral Nub 28 364-371... 

Although cytochalasin B normally functions as a reversible inhibitor of glucose transport, upon exposure to ultraviolet light a small proportion of the bound cytochalasin B molecules become covalently linked to the transporter protein [128-130]. Photolabelling is inhibitable by D-glucose and other transported sugars but not by... 

Dawson, P. A., et al. Sequence and functional analysis of GLUT10 a glucose transporter in the Type 2 diabetes-linked region of chromosome 20ql2—13.1. Mol. Genet. Metab. 2001, 74, 186-199. 

Olson, A. L. and J. E. Pessin. Structure, function, and regulation of the mammalian facilitative glucose transporter gene family. Annu. Rev. Nutr. 1996, 36, 235-256. 

Gould GW, Holman GD. The glucose transporter family structure, function and tissue specific expression. Biochem J 1993 295 329-341. 

Hebert, D. N. and Carruthers, A. (1992) Glucose transporter oligomeric structure determines transporter function. Reversible redox-dependent interconversions of tetrameric, and dimeric GLUT1. J. Biol. Chem. 267, 23829-23838. 

Other Toxicity Concerns. Additional toxicity concerns include interference with normal metabolism and function of mucosal cells, for example, water absorption by these cells [80]. The unconjugated bile acids are known to block amino acid metabolism [81] and glucose transport [82]. There is a possibility of biotransformation of these enhancers to toxic or carcinogenic substances by hepatic monooxygenases [83]. Absorption of permeation enhancers into the systemic circulation can also cause toxicity, for example, azone [84] and hexamethylene lauramide [85] which are absorbed... 

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