Family structures

Flower D.R. (1996). The lipocalin protein family structure and function. Biochem J 318, 1-14. 

Pakhomov AA, Martynov VI (2008) GFP family structural insights into spectral tuning. Chem Biol 15 755-764... 

Gould GW, Holman GD. The glucose transporter family structure, function and tissue specific expression. Biochem J 1993 295 329-341. 

Matias PM, Coelho R, Pereira lA, et al. 1999. The primary and three-dimensional structures of a nine haem cytochrome c from Desulfovibrio desulfuricans ATCC 2111A reveal a new member of the Hmc family. Structure 7 119-30. 

Second, family structures change over time and so too do family processes, sometimes for the better. The past, although significant, does not have to determine the future. 

Wang HY, Friedman E Chronic lithium desensitization of autoreceptors mediating serotonin release. Psychopharmacology 94 312-314, 1988 Wang HY, Friedman E Lithium inhibition of protein kinase C activation-induced serotonin release. Psychopharmacology 99 213-218, 1989 Wank SA, Pisegna JR, de Weerth A Brain and gastrointestinal cholecystokinin receptor family structure and functional expression. Proc Natl Acad Sci USA 89 8691-8695, 1992... 

The therapy model uses elements of both structural and strategic family therapy. Structural family therapy derives its name from the perceived importance of family composition, particularly as a hierarchy, and how this hierarchical system is organised. For example, a family with a weak and ineffectual father would be subject to an imbalance in family structure. The therapist s main objective is to identify the imbalance and to intervene by emphasising the importance of the father and his role in the family, that is, elevating his importance. Structural family therapy is widely associated with Salvador Minuchin, who used it extensively in the treatment of anorectic families . Only a cursory summary is presented here. Interested readers will find these techniques covered more fully in Minuchin and Fishman (1981). 

In order to assess the family structure, the following techniques may be useful ... 

Carson-Jurica, M.A., Schrader, W.T., O Malley, B.W. (1990) Steroid receptor family—structure and functions. Endocr. Rev. 11, 201-220. 

Kaufmann, S. H. (1989) Additional members of the rat liver lamin polypeptide family, structural and immunological characterization. J. Biol. Chem 264, 13,946-13,955. 

Halestrap AP, Price NT. 1999. The proton-linked monocarboxylate transporter (MCT) family Structure, function and regulation. Biochem J 343 Pt 2 281-299. 

Kielty, C. M., and Grant, M. E. (2002). The Collagen Family Structure Assembly and Organization in the Extracellular Matrix. In Connective Tissue and its Heritable Disorders, (P. M. Royce andB. Steinmann, Eds.), pp. 159-222. Wiley-Liss, New York. 

G. Schneider, Crystal structure of transaldolase B from Escherichia coli suggests a circular permutation of the a/ P-barrel within the class I aldolase family, Structure 1996, 4, 715-724. 

Sack, S., Kull, F. J., and Mandelkow, E. (1999). Motor proteins of the kinesin family Structures, variations and nucleotide binding sites. Eur.J. Biochem. 262, 1-11. 

Yousef GM, Diamandis EP. The new human tissue kallikrein gene family Structure, function, and association to disease. Endocr Rev 2001 22 184-204. 

It is important to minimize or control for the impact of confounding variables in any study. In order to do so, it is imperative that all possible variables that may have an effect on the primary outcome be identified. These usually include demographic variables such as age, sex, income level, education level, and ethnicity. Health-related variables such as comorbidities and severity of illness should also be recorded. Variables also may be identified that cannot be measured. These may include outside education, changes in family structure or support system, and drastic changes in health status not related to the pertinent disease state. 

Klagsbrun M. The fibroblast growth factor family structural and biological properties. Prog Growth Factor Res 1989 1(4) 207-235. 

Pessin JE, Bell GI (1992), Mammalian facilitative glucose transporter family. Structure and molecular regulation, Annu. Rev. Physiol. 54 911-930. 

Anderson, O.D., Hsia, C.C., Torres, V. 2001. Wheat y-gliadin genes Characterization of ten new sequences and further understanding of y-gliadin gene family structure. TheorAppl Genet 103 323-330. 

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