Glucose sensors fermentation process

These examples indicate the in situ applicability of enzyme electrodes however, numerous problems have still to be solved. At present, coupling of enzyme sensors for fermentation control in a bypass arrangement appears to be more favorable [412]. Following this concept, an invertase thermistor incorporating a sterilizable filter unit has been developed [413] for the monitoring of alcoholic fermentation by immobilized yeast cells. Another thermistor has been successfully used for on-line glucose measurement under real cultivation conditions of Cephalosporium acremonium [414]. Similar calorimetric devices are suitable for other fermentation processes and in environmental analysis. 

When enzyme sensors are combined with FIA they have applications in medicine and the food produce industry. For example, FIA has been combined with the glucose oxidase electrode to determine glucose in blood [270], with the choline oxidase electrode for the determination of cholinesterase in serum [271], and with a bienzyme electrode that uses choline oxidase and phospholipase for the determination of phospholipids in serum [272]. The technique has also been used with an alcohol oxidase electrode to determine alcohol in drinks (for example, beers) [273], or with a glucose oxidase electrode to determine glucose [274] in various foodstuffs [275] or in fermentation processes [276]. 

Su Y.C. and Chen C.Y. (1987) A glucose sensor for fermentation process monitoring sensor fabrication and its batch operation characteristics. Proc. Natl. Sci. Counc. B. ROC, 11, 10-17. 

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