Gluconolactone 6-phosphate

Glucose- 1-phosphate Glucose-6-phosphate Gluconolactone-6-phosphate Ethyl Glucose Vinyl... 

Fio. 9. The dehydrogenation of glucose-6-phosphate to 6-phosphogluconic acid via gluconolactone-6-phosphate. 

Table 6 Hsts the leavening acids and the corresponding rates of reaction. The leavening acids most frequently used iaclude potassium acid tartrate, sodium aluminum sulfate, 5-gluconolactone, and ortho- and pyrophosphates. The phosphates iaclude calcium phosphate [7758-23-8] CaHPO, sodium aluminum phosphate, and sodium acid pyrophosphate (66).

Glucose 6-phosphate Gluconolactone 6-(p) Gluconate 6-phosphate Ribulose 5-phosphate... 

This enzyme [EC 1.1.1.49] catalyzes the NADP -depen-dent reduction of o-glucose 6-phosphate that yields 6-phospho-D-gluconolactone, NADPH, and a proton. 

This procedure could in principle open the way, inter alia, to the phosphono analog of D-glucose 1-phosphate simply by reacting the gluconolactone 56 with LiCH2PO(OMe)2 and then reducing Ae obtained lactol 59. Unfortunately the lactol phosphonate 59 was inert to this reduction (Scheme 16). 

The reaction mixture contained in a final volume of 0.1 mL, 0.1 M sodium phosphate buffer (pH 6.8), 1.0 mM tryptamine, 5 mM secologanin, and 3 mM dithiothreitol. To inhibit glucosidase activity, 100 mM D(+)-gluconic acid-5-D-gluconolactone was included. The incubation was started by addition of 10 /xL of enzyme. After 30 minutes of incubation at 30°C, the reaction was stopped by addition of 0.1 mL of 5% trichloroacetic acid. Before centrifugation, 25 /xL of 8 mM codeine hydrochloride was added as the internal standard. HPLC analysis was performed on 4 /xL aliquots. With enzyme purified to a specific activity of 710 pkat per milligram of protein, the reaction was linear with time for 1 hour and with protein up to at least 50 /xg of protein during a 20-minute incubation period. 

A. glucose-6-phosphate dehydrogenase, NADH, gluconolactone hydrolase, 6-phosphogluconate dehydrogenase, ribulose-5-phosphate epimerase... 

Uses Used in formulations that are replacements for phosphates in detergents Gluconolactone... 

Cl 1-12 isoparaffin Cl 1-13 isoparaffin Deodorized kerosene trans-1,2-Dichloroethylene 2,3-Dihydrodecafluoropentane Ditallow dimonium chloride Ethylene carbonate Ethylene chlorohydrin Gluconolactone Isohexane Methyl acetate Naphtha, hydrotreated light Pentasodium triphosphate, hexahydrate 2-Phosphonobutane tricarboxylic acid-1,2,4 Propylene carbonate Sodium borate decahydrate Stearyl hydroxyethyl imidazoline 2,2,3,3-Tetrafluoro-1-propanol Trisodium phosphate, chlorinated Xylene cleaner ingredient Ammonium biborate cleaner ingredient, engine Cresylic acid Xylenol cleaner ingredient, industrial Butyl acid phosphate Sodium hydroxide cleaner mfg. 

Calcium phosphate tribasic milkstone prevention, dairy industry Gluconolactone mill scale removal Citric acid milling aid Dodoxynol-9 milling aid, dyes... 

Disodium ethanoldiglycine Tetrapotassium pyrophosphate sequestrant, canned goods Gluconolactone sequestrant, chemical cleaning Pentasodium pentetate sequestrant, chemicals Ammonium polyaspartate sequestrant, cleaners Ammonium lignosulfonate Sodium lignosulfonate Sodium nitrilotris (methylene phosphate) sequestrant, cleaning Sodium hexametaphosphate Tetrasodium EDTA... 

Gluconolactone sequestrant, dandruff shampoo Distarch phosphate sequestrant, deinking... 

The first step in the HMP pathway (Fig. 17.6) is the oxidation of glucose-6-phosphate by an NADP+-dependent dehydrogenase. The product, 6-phospho-gluconolactone, is converted to 6-phosphogluconic acid by a lactonase. A second oxidative step mediated by 6-phosphogluconic acid dehydrogenase. 

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