Gloves permeability

Study raises questions about glove permeability. CDC AIDS Weekly 11 19-20, 1988. 

In humans VCD is considered to be a mild to moderate skin irritant, although occasional instances of marked irritation have been reported. In one case severe vesiculation of the skin of both feet occurred when a worker wore shoes previously contaminated with VCD. A single case of allergic contact dermatitis has also been reported in a worker whose gloves were permeable to VCD. Systemic illness in humans has not been reported in association with exposure. ... 

This substance has extensive lipid solubility and is absorbed immediately by the skin. Additionally, DMM is able to penetrate many materials including plastic and rubber compounds such as latex, polyvinyl chloride, and neoprene in a matter of seconds. In permeability tests, a Silver Shield glove of a flexible, plastic-laminate, offered skin protection from DMM for 4h. This chemically resistant glove, when worn under an outer glove that is resistant to abrasion and tears, may provide limited protection for direct handling of DMM. 

Wearing gloves, the doctor rolls a sheet of sandpaper around a round object (e.g. a bottle of pre-peel cleanser). The skin is held taut with one hand, and intersecting, careful, gentle and repeated passes are made with the sandpaper. Pressure must be firm and even. If the pressure is too light, the skin will not be abraded properly. On the other hand, if the pressure is too firm, it will take off more skin and make it too permeable. 

The best results are achieved when the skin has been prepared for 15 days beforehand see Chapter 2. If the skin has been prepared with tretinoin or alpha-hydroxy acids (AHAs), if the patient has used products (benzoyl peroxide) or techniques (scrub, or abrasion with a massage glove) that increase the permeability of the stratum corneum, the resorcinol paste should not be left on too long. 

Skin can be an important route of JP-8 exposure. Aircraft fuel-maintenance workers may be exposed to liquid jet fuel for more than 10 min, which gives ample opportunity for dermal exposure. Except for chemical-resistant eyewear, footwear,gloves, and cotton coverall jumpsuits, which are permeable to JP-8, there is little protection of skin. Prolonged JP-8 skin contact can induce irritation, contact dermatitis, and sensitization (Wolfe et al. 1997 Ullrich 1999). 

J DeGroot-Kosolcharoen, JM Jones. Permeability of latex and vinyl gloves to water and blood. Am J Infect Control 17 196-201, 1989. 

JM Miller, CS Collier, NM Griffith. Permeability of surgical rubber gloves. Am J Surg 124 57-59, 1972. 

DW Ramsing, A Fullerton. Permeability of protective gloves to sodium lauryl sulfate. A release cambers used as an in vitro test system. Skin Res Technol 2 37-39, 1996. 

HEMA is a known contact allergen [70,71], but despite this there do not seem to have been any reports of dermatitis among dental personnel, either dentists or then-assistants [61]. Latex gloves are inadequate to protect the skin because they are permeable to HEMA [79]. The volatility HEMA may also cause problems with these materials, and inhalation of the vapour should be avoided [61]. There are anecdotal reports of dental personnel developing allergies to resin-modified glass-ionomers, but again there seem to be no detailed reports or case studies in the literature about this. 

H. Andreasson, A. Boman, S. Johnsson, S. Karlsson, L. Barregard, On permeability of methyl methacrylate, 2-hydroxyethyl methacrylate and triethylenegycol dimethacrylate through protective gloves in dentistry, Eur. J. Oral Sci. Ill (2003) 529-535. 

Mott types of gloves are to a certain extent permeable to dimethyl acetamide. Alcohol consumption inadvisable after exposure. Depending on the degree of exposure, regular medical checkups are advisable. Absorbed very rapidly through the skin. 

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