Gene expression detection

Burris TP, Pelton PD, Zhou L, et al. A novel method for analysis of nuclear receptor function at natural promoters peroxisome proliferator-activated receptor y agonist actions on a P2 gene expression detected using branched DNA messenger RNA quantitation. Mol Endocrinol 1999 13 410—417. 

Gaunt, S.J. 2001. Gradients and forward spreading of vertebrate Hox gene expression detected by using a Hox/lacZ transgene. Dev. Dyn. 221, 26-36. 

Wu, B. (2005). Differential Gene Expression Detection Using Penalized Linear Regression Models the Improved SAM Statistics. Bioinjbrmatics, Vol. 21, pp. 1565-1571. 

Kieffer TL, Finucane MM, Nettles RE, Quinn TC, Broman KW, Ray SC, Persaud D, SUiciano RF (2004) Genotypic analysis of HIV-1 drug resistance at the limit of detection virus production without evolution in treated adults with undetectable HIV loads. J Infect Dis 189(8) 1452-1465 Kinoshita S, Su L, Amano M, Timmerman LA, Kaneshima H, Nolan GP (1997) The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells. Immunity 6(3) 235-244... 

Brazil GM, L Kenefick, M Callanan, A Haro, V de Lorenzo, DN Dowling, F O Gara (1995) Constrnction of a rhizosphere psendomonad with potential to degrade polychlorinated biphenyls and detection of bph gene expression in the rhizosphere. Appl Environ Microbiol 61 1946-1952. 

In contrast, inactivity of muscle gene expression and elevated DNA content of infected cell nuclei did not change detectably with MBZ treatment, which may indicate that these host cell parameters are not chronically regulated by the parasite. 

Polymorphism A common (i.e., at least 1% prevalence of the minor allele in the population) sequence variation observed in an individual at a polymorphic site. Polymorphisms include nucleotide substitutions, insertions, deletions and microsatellites. They may be functional or silent, i.e., they do not result in detectable differences in gene expression or protein function. 

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