Genes vomeronasal receptors

Del Punta K., Rothman A., Rodriguez I. and Mombaerts P. (2000). Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse. Genome Res 10, 1958-1967. 

Lane R., et al. (2002). Sequence analysis of mouse vomeronasal receptor gene clusters reveals common promoter motifs and a history of recent expansion. Proc Natl Acad Sci 99, 291-296. 

Saito H., Mimmack M., Keveme E.B., Kishimoto J. and Emson P. (1998). Isolation of mouse vomeronasal receptor genes and their co-localization with specific G-protein messenger RNAs. Molec Brain Res 60, 215-227. 

L. and Mombaerts, P. (2002) Deficient pheromone responses in mice lacking a cluster of vomeronasal receptor genes. Nature 419, 70-74. 

The knowledge of chemosensory communication has grown rapidly over the last ten years since the identification of the first olfactory receptor genes. The subsequent cloning of genes for rodent vomeronasal receptors, which are important in pheromone detection, has revealed an unexpected diversity of around 250 receptors belonging to two structurally different classes. 

Mundy NI, Cook S (2003) Positive selection during the diversification of class I vomeronasal receptor-like (V1RL) genes, putative pheromone receptor genes, in human and primate evolution. Mol Biol Evol 20 1805-1810... 

Rodriguez I, Mombaerts P (2002) Novel human vomeronasal receptor-like genes reveal species— specific families. Curr Biol 12 R409-411... 

Zhang X, Rodriguez I, et al. (2004a) Odorant and vomeronasal receptor genes in two mouse genome assemblies. Genomics 83(5) 802-811... 

Shi P, Zhang J (2007) Comparative genomic analysis identifies an evolutionary shift of vomeronasal receptor gene repertoires in the vertebrate transition from water to land. Genome Res 17 166-174... 

Rodriguez I, Feinstein P, Mombaerts P (1999) Variable patterns of axonal projections of sensory neurons in the mouse vomeronasal system. Cell 97 199-208 Rodriguez I, Greer CA, Mok MY, Mombaerts P (2000) A putative pheromone receptor gene expressed in human olfactory mucosa. Nat Genet 26 18-19 Rodriguez I, Del Punta K, Rothman A, Ishii T, Mombaerts P (2002) Multiple new and isolated families within the mouse superfamily of Vlr vomeronasal receptors. Nat Neurosci 5 134-140... 

Shi P, Bielawski JP, Yang H, Zhang YP (2005) Adaptive diversification of vomeronasal receptor 1 genes in rodents. J Mol Evol 60 566-576... 

Yang H, Shi P, Zhang YP, Zhang J (2005) Composition and evolution of the V2r vomeronasal receptor gene repertoire in mice and rats. Genomics 86 306-315 Yoon H, Enquist LW, Dulac C (2005) Olfactory inputs to hypothalamic neurons controlling reproduction and fertility. Cell 123 669-682... 

In vertebrates, the genes involved in olfactory reception are distributed in many multigenic families, including OR, expressed in the olfactory epithelium, and the vomeronasal receptors (VR), expressed in the auxiliary olfactory organ called the vomeronasal organ (see Chapter 3). These gene... 

Asano-Miyoshi M., Suda T., Yasuoka A., et al. (2000). Random expression of main and vomeronasal olfactory receptor genes in immature and mature olfactory epithelia of Fugu rubripes. J Biochem 127, 915-924. 

Dulac C. and Axel R. (1998). Expression of candidate pheromone receptor genes in vomeronasal neurons. Chem Senses 23, 467-475. 

Mombaerts, P. Genes and ligands for odorant, vomeronasal and taste receptors. Nat. Rev. Neurosci. 5 263-278, 2004. 

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