Gene expression glutamine synthetase

Miao, G.-H., Hirel, B., Marsolier, M.C., Ridge, R.W. Verma, D.P.S. (1991). Ammonia-regulated expression of a soybean gene encoding glutamine synthetase in transgenic Lotus corniculatus and tobacco. The Plant Cell 3, 11-22. 

Kozaki, A., Sakamoto, A., Tanaka, K. Takeba, G. (1991). The promoter of the gene for glutamine synthetase from rice shows organ-specific and substrate-induced expression in transgenic tobacco plants. Plant and Cell Physiology 32, 353-8. 

Bennett, M.J., Lightfoot, D.A. Cullimore, J.V. (1989). cDNA sequence and differential expression of the gene encoding the glutamine synthetase y polypeptide of Phaseolus vulgaris L. Plant Molecular Biology 12, 553-65. 

Cock, J.M., Mould, R.M., Bennett, M.J. Cullimore, J.V. (1990). Expression of glutamine synthetase genes in roots and nodules of Phaseolus vulgaris following changes in the ammonium supply and infection with various Rhizobium mutants. Plant Molecular Biology 14, 549-60. 

Edwards, J.W. Coruzzi, G.M. (1989). Light and photorespiration act in concert to regulate the expression of the nuclear gene for chloroplast glutamine synthetase. The Plant Cell 1, 241-8. 

Forde, B.G., Day, H.M., Turton, J.F., Shen, W.-J., Cullimore, J.V. Oliver, J.E. (1989). Two glutamine synthetase genes from Phaseolus vulgaris L. display contrasting developmental and spatial patterns of expression in transgenic Lotus corniculatus plants. The Plant Cell 1, 391-401. 

Primary structure and differential expression of glutamine synthetase genes in nodules, roots and leaves of Phaseolus vulgaris. The EMBO Journal 5, 1429-35. 

Tingey, S.V., Walker, E.L. Coruzzi, G.M. (1987). Glutamine synthetase genes of pea encode distinct polypeptides which are differentially expressed in leaves, roots and nodules. The EMBO Journal 6, 1-9. 

Gebhardt, C., Olivier, J.E., Forde, B.G., Saarelainen, R. Miflin, B.J. (1986). Primary structure and differential expression of glutamine synthetase genes in nodules, roots and leaves of Phaseolus vulgaris. The EMBO Journal 5, 1429-35. 

Sengupta-Gopalan, C. Pitas, J.W. (1986). Expression of nodule-specific glutamine synthetase genes during nodule development in soybeans. Plant Molecular Biology 7, 189-99. 

Bebbington CR, Renner G, Thomson S, King D, Abrams D, Yarranton GT (1992), High level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selectable marker, Biotechnology 10 169-175. 

Cockett, M.I., C.R. Bebbington, and G.T. Yarranton. 1990. High level expression of tissue inhibitor of metallopro-teinases in Chinese hamster ovary cel Is using glutamine synthetase gene amplification. Biotechnol (NY) 8 662-667. 

Wyman, M. (1999). Diel rhythms in ribulose-l,5-bisphosphate carboxylase/oxygenase and glutamine synthetase gene expression in a natural population of marine picoplanktonic cyanobacteria Syne-chococais spp.). Appl. Environ. Microbiol. 65, 3651—3659. 

The next most commonly used cell lines are the murine myeloma cell lines such as NS(T and Sp2/0. The NSO cell line is deficient for the glutamine synthetase gene, and the presence of glutamine synthetase (GS) gene on vectors has been used for the selection of stably integrated expression cassettes. ... 

Cockett, M.L, Bebbington, C.R., and Yarranton, G.T., High level expression of tissue inhibitor of metalloproteinases in Chinese hamster ovary cells using glutamine synthetase gene amphfication. Biotechnology (NY), 8, 662, 1990. 

Patejunas, G. Young, AP. (1990). Constitutive and glucocorticoid-mediated activation of glutamine synthetase gene expression in developing chicken retina. J. Biol. Chan., 265, 15280-5. 

The production of therapeutic proteins in mammalian cells requires the expression of product-specific genes in the host cell line. The dihydrofolate reductase (DHFR) and the glutamine synthetase (GS) expression vector systems are most... 

Desjardins P, Butterworth RE. The peripheral-type benzodiazepine ( 3) receptor in hyperam-monemic disorders. Neurochem. Int., 41, 109-114, 2002 Desjardins P, Bandeira P, Raghavendra Rao VL, Ledoux S, Butterworth RF. Increased expression of the peripheral-type benzodiazepine receptor-isoquinohne carboxamide binding protein in mRNA brain following portacaval anastomosis. Brain Res., 758, 255-258, 1997 Desjardins P, Rama Rao VK, Michalak A, Rose C, Butterworth RF. Effect of portacaval anastomosis on glutamine synthetase protein and gene expression in brain, liver and skeletal muscle. Metab. Brain Dis., 14, 273-282, 1999... 

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