Gastroenteritis absorption

Marchi E, Montecchi L, Venturini AP, Mascel-lani G, Brufani M, Cellai L 4-Deoxypyri-do[l, 2 l,2]imidazo[5,4-c]rifamycin SV derivatives. A new series of semisynthetic rifamycins with high antibacterial activity and low gastroenteric absorption. J Med Chem 1985 28 960-963. 

Succimer has also been effective in animal models and has a higher therapeutic index than dimercaprol. However, because it is available in the United States only for oral administration, its use may not be advisable in the initial treatment of acute arsenic poisoning, when severe gastroenteritis and splanchnic edema may limit absorption by this route. 

In general, the only treatment available for exposure to cyanobacterial algal toxins is supportive medical treatment after complete removal from exposure. If the exposure was oral, administration of activated carbon to decrease gut absorption may be efficacious if given within hours of exposure. Based on past outbreaks, monitoring of volume, electrolytes, liver and kidney function should all be considered in the case of acute gastroenteritis associated with some of the cyanobacterial algal toxins. 

Human Toxicity Highly toxic hy ingestion or absorption from skin and mucous membranes severe gastroenteritis, Kpbitis, collapse, death may occur. Clinical Toxicology of Commercial Products, R. E. Gosselin et ai. Eds. (Williams Wilkins, Baltimore, 4th ed, 1976) Section II, p 173. tmaf cat Vesicant. 

Human Toxicity fngestion may cause renal damage, severe gastroenteritis. Application to large areas of skin may cause renal irritation by percutaneous absorption. Inadvertent conjunctival contact frequently produces conjunctivitis. Allergic reaction of skin has been reported. 

Intestinal diseases that injure the absorptive cells of the intestinal villi diminish lactase activity along the intestine, producing a condition known as secondary lactase deficiency. Kwashiorkor (protein malnutrition), colitis, gastroenteritis, tropical and... 

Signs and symptoms Acute iron intoxication is most common in children and usually occure as a result of accidental ingestion of iron supplementation tablets. Depending on the dose, necrotizing gastroenteritis, shock, metabolic acidosis, coma, and death may result. Chronic toxicity occurs most often in individuals who must receive frequent transfusions (eg, patients with sickle cell anemia) and in those with hemochromatosis, an inherited abnormality of iron absorption. 

The treatment of choice in acute arsenic poisoning is intramuscular dimercaprol. While succimer is less toxic than dimercaprol, it is available only in an oral formulation and its absorption may be impaired due to the severe gastroenteritis that occurs in acute poisoning with arsenic. The answer is (B). 

Forbidden in Norway and Austria Low absorption from gastroenteric system Forbidden in Norway, United States, Australia, Japan Allergic reactions Forbidden in Norway, United States, Switzerland, Japan, Sweden... 

Holm S, Andersson Y, Gothefors L, Lindbert T. 1992. Increased protein absorption after gastroenteritis in children. Acta Paediatr 81 585-588. 

Malabsorption of vitamin A occurs associated with diarrhea, intestinal infections, and infestations (Rosenberg et aL, 1977 Mansour et aL, 1979). Children with a recent history of diarrhea are at higher risk of developing clinical evidence of deficiency than those without (Sommer, 1982a). Sivakumar and Reddy (1972, 1978) used labeled vitamin A to demonstrate a depressed absorption of vitamin A in acute gastroenteritis and in respiratory infections. Presumably this was primarily due to excessively rapid passage more than to a defective intraluminal hydrolytic system, because providing a vitamin A supplement to children with diarrhea results in improved absorption (Sivakumar and Reddy, 1978). 

These changes are indicative of the impairment of absorption of labelled lysine in the gastroenteric tract of chronic-enterocolitis patients when given the whole egg white. This fact seems to be... 

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