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Gangliosides, biosynthesis

It was also demonstrated that ceramides derived from sphingomyelin breakdown mediated by ASM are used for ganglioside biosynthesis, up to the generation of GD3. Indeed, lymphoblastoid cells derived from Niemann-... [Pg.297]

Kolter, T., Proia, R.L. and Sandhoff, K. (2002) Combinatorial ganglioside biosynthesis, journal of Biological Chemistry 277, 25859-25862. [Pg.420]

Induction of Ganglioside Biosynthesis in Cultured Cells by Butyric Acid... [Pg.223]

NEUROTROPHIC AND NEUROPROTECTIVE ACTIONS OF AN ENHANCER OF GANGLIOSIDE BIOSYNTHESIS... [Pg.319]

In this review, I summarize our approaches to explore a new therapeutic intervention for the treatment of neurological disorders by enhancing the ganglioside biosynthesis. [Pg.321]

Inokuchi, J., Mizutani, A., Jimbo, M., Usuki, S., Yamagishi, K., Mochizuki, H., Muramoto, K., Kobayashi, K., Kuroda, Y., Iwasaki, K., Ohgami, Y., and Fujiwara, M. (1997). Up-regulation of ganglioside biosynthesis, functional synapse formation, and memory retention by a synthetic ceramide analog (1-PDMP). Biochem. Biophys. Res. Commun. 237, 595—600. [Pg.334]

Inokuchi, J., Kuroda, Y., Kosaka, S., and Fujiwara, M. (1998). L-threo-1 -phenyl-2-decanoylamino-3-morpholino-1-propanol stimulates ganglioside biosynthesis, neurite outgrowth and synapse formation in cultured cortical neurons, and ameliorates memory deficits in ischemic rats. Acta Biochim. Pol. 45, 479—492. [Pg.334]

Usuki, S., Hamanoue, M., Kohsaka, S., and Inokuchi,J. (1996). Induction of ganglioside biosynthesis and neurite outgrowth of primary cultured neurons by L-threo-1 -phenyl-2-decanoylamino-3-mor-pholino-1 -propanol. J. Neurochem. 67, 1821-1830. [Pg.336]

Fig. 1.4.7. Early steps in combinatorial ganglioside biosynthesis [9]. The sites of (indirect) inhibition by 11 and 12 are indicated. Abbreviations Cer, ceramide, N-acylsphingosine Clc, glucose Gal, galactose GalNAc, N-acetylgalactosamine NeuAc, N-acetylneuraminic acid SAT, sialyltransferase GalNAcT, N-acetylgalactosaminyltransferase ... Fig. 1.4.7. Early steps in combinatorial ganglioside biosynthesis [9]. The sites of (indirect) inhibition by 11 and 12 are indicated. Abbreviations Cer, ceramide, N-acylsphingosine Clc, glucose Gal, galactose GalNAc, N-acetylgalactosamine NeuAc, N-acetylneuraminic acid SAT, sialyltransferase GalNAcT, N-acetylgalactosaminyltransferase ...
Glycosphingolipid Ganglioside Biosynthesis Catabolism Nervous system Endoplasmic reticulum Golgi Glycosyltransferase Glycosidase Lipid-storage disorder... [Pg.1672]

Glycosyltransferase Genes Involved in Ganglioside Biosynthesis and their Transcriptional Regulation... [Pg.1677]

Kolter T, Proia RL, Sandhoff K (2002) Combinatorial ganglioside biosynthesis. J Biol Chem 277 25859-25862... [Pg.1689]

K. Furukawa Recent progress in the analysis of gangliosides biosynthesis. Nagoya Journal of Medical Science 61 27 (1998). [Pg.329]

Anic M., and Mesaric M. (1998). The influence of sex steroid hormones on ganglioside biosynthesis in rat kidney. Biol Chem 379, 693-697. [Pg.404]

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