Fructooligosaccharide effects

ROBERFROID M B (1996) Functional effects of food components and the gastrointestinal system chicory fructooligosaccharides. Nutr Rev. 54 S38-42. 

Perin S., Grill J.P. and Schneider F. (2000). Effects of fructooligosaccharides and their... 

Waldroup, A.L., Skinner, J.T., Hierholzer, R.E. and Waldroup, P.W. (1993) An evaluation of fructooligosaccharide in diets for broiler chickens and effects on Salmonellae contamination of carcasses. Poultry Science 72, 643-650. 

In Japan, where mineral deficiency can be a nutritional problem, the beneficial effects of fructooligosaccharides on calcium absorption have been recognized in the labeling on dietary supplements since 1999 (Hidaka et al., 2001). 

Inulin and fructooligosaccharides are more effective at lowering serum levels of lipids (triglycerides) than cholesterol, with inulin more effective than short-chain fructooligosaccharides in... 

Fukata, T., Sasai, K., Miyamoto, T., and Baba, E., Inhibitory effects of competitive exclusion and fructooligosaccharides, singly and in combination, on Salmonella colonization of chicks, J. Food Prot., 62, 229-233, 1999. 

Howard, M.D., Gordon, D.T., Pace, L.W., Garleb, K.A., and Kerley, M.S., Effects of dietary supplementation with fructooligosaccharides on colonic microbiota populations and epithelial cell proliferation in neonatal pigs, J. Pediatr. Gastroenterol. Nutr., 21, 297-303, 1995. 

Luo, J., Rizkalla, S.W., Alamowitch, C., Boussairi, A., Blayo, A., Barry, J.L., Laffitte, A., Guyon, F., Bomet, F.R., and Slama, G., Chronic consumption of short-chain fructooligosaccharides by healthy subjects decreased basal hepatic glucose production but had no effect on insulin-stimulated glucose metabolism, Am. J. Clin. Nutr., 63, 939-945, 1996. 

Moro, G., Minoli, I., Mosca, M., Fanaro, S., Jelinek, J., Stahl, B., and Boehm, G., Dosage-related bifidogenic effects of galacto- and fructooligosaccharides in formula-fed term infants, J. Pediatr. Gastroenterol. Nutr., 34, 291-295, 2002. 

Nemcova, R., Bomba, A., Gancarikova, S., Herich, R., and Guba, P., Study of the effect of Lactobacillus paracasei and fructooligosaccharides on the faecal microflora in weaning piglets, Berl. Milnch. Tierarztl. Wschr., 112, 225-228, 1999. 

Ohta A., Baba, S., Takizawa, T., and Adachi, T., Effects of fructooligosaccharides on the absorption of magnesium in the magnesium-deficient rat model, J. Nutr. Sci. Vitaminol., 40, 171-180, 1994. 

Oike, H., Matsuoka, R., Tashiro, Y., Hirayama, M., Tamura, Z., and Yamazaki, S., Effect of Bifidobacterium-monoassociation and feeding of fructooligosaccharides on lethal activity of enterohemorrhagic Escherichia coli 0157 in germ-free mice, Bifidobacteria Microflora, 18, 101-109, 1999. 

Tominaga, S., Hirayama, M., Adach, T., Tokunaga, T., and Lino, H., Effects of ingested fructooligosaccharides on stool frequency in healthy female volunteers a placebo controlled study, Biosci. Microflora, 18, 49-53, 1999. 

For the above reasons, the effect of pH and ionic shength on the immobihzation of the fructosyitransferase from A. aculeatus on Sepabeads EC-EP was studied. Although this enzyme constitutes only a minor percentage (0.4% w/w) of the total proteins present in Pectinex Ulha SP-L, the commercial preparation was used directly (without enzyme purification) in order to develop a simple process that could be easily scaleable in the industry. It was considered that, although the other proteins present in Pectinex Ulha SP-L could also be immobilized in Sepabeads EC-EP, they would not interfere in fructooligosaccharide synthesis experiments. 

Tuohy KM, Kolida S, Lustenberger A, Gibson GR. The prebiotic effects of biscuits containing partially hydrolyzed guar gum and fructooligosaccharides - a human volunteer study. Br Nutr. 2001 86 341-348. 

Fukasawa, T., Murashima, K., Matsumoto, 1., and Hosono, A. 2007. Identiflcation of marker genes for intestinal immunomodulating effect of a fructooligosaccharide by DNA microarray analysis. J Agric Food Chem 55 3174-3179. 

Nemcova, R., Bomba, A., Gancarcikova, S., et al. (2007) Effects of the administration of lactobacilli, maltodextrins and fructooligosaccharides upon the adhesion of E. coli 08 K88 to the intestinal mucosa and organic acid levels in the gut contents of piglets. Vet Res Communic 31, 791-800. 

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