Formate reaction with

Ethylene carbonate, reaction with potassium thiocyanate, 42, 59 Ethylene sulfide, 42, S9 Ethyl formate, reaction with cyclo-hexylamine, 41, 14 Ethyl- -hexylamine, 43, 47 5-(2-Ethylhexyl)-l,2,3,4,5-pentachloro-cyclopentadiene, 43, 93 Ethylhydrazinium hydrogen oxalate,... 

Formation, reaction with phosphines, phosphites, CO and CH3CN 6.5.3.4 i682sB2FeS... 

Formation, reaction with LiCo(CO)4, AuJ(p-MeC6H5)3P]8[B(C6H5)4]2... 

AugKC HsljPlglNOjlz Formation, reaction with [RhCl(CgH4)2]2 8.2.1.3... 

Aldehyde particles are spontaneously reactive with hydrazine or hydrazide derivatives, forming hydrazone linkages upon Schiff base formation. Reactions with amine-containing molecules, such as proteins, can be done through a reductive amination process using sodium cyanoborohydride (Figure 14.21). 

Among typical carbon-carbon bond (C-C) formation reactions with carbenes, the cyclopropanation reaction with olefins has been well studied including its application to industrial processes. The second typical reaction of carbenes is the insertion reaction into the carbon-hydrogen bond (C-H) which seems to be a direct and efficient C-C bond forming reaction. However, its use for synthetic purpose has often been limited due to low selectivity of the reactions.3... 

Post-reactions of polyacrylamide to introduce anionic, cationic, or other functional groups are often attractive from a cost standpoint. This approach can suffer, however, from side reactions resulting in cross-linking or the introduction of unwanted functionality. Reactions include hydrolysis, sulfoiiielliylatioii, melliylol formation, reaction with other aldehydes, transamidadon, Hoffman degradation, and reaction with chlorine. 

The enol acetate 77 of 3,4-dihydro-7-methoxy-5-methyl-l-(2l/)-naphthalenone was converted to the acid 78 by ozonolysis and hydrolysis and this by a Wittig reaction with a-methoxyethyltriphenyl-phosphonium chloride gave 79. Compound 79 was converted into 80 by a series of reactions, five in number, which in turn was converted into 81 by reaction with potassium in -butanol. The methyl ester of compound 81, one isomer of which was recognized as that having the correct stereo structure, was converted to 82 by heating with acetic anhydride and 10-camphorsulfonic acid. Subsequent steps involved ozonization, reaction with V,iV -carbonyldiimidazole, lactam formation, reaction with pyridinium bromide perbromide, reaction with sodium hydride, and a further series in which (+ )-oxodendrobine (83) was ultimately obtained. Reduction of the latter to ( )-dendrobine... 

At the same time, some case are known when it is possible to carry out complex-formation reactions with N,S-donor chelating systems having a free SH group, for example (3.51) [61], (3.52) [62], (3.53) [63], and (3.54) [64] ... 

The chemical resolution process of Scheme 6 was developed into an economically favorable one by the ready recycle of both the FPA resolving agent and the combined (mostly S) amine fractions. FPA, which was prepared by methyl formate reaction with L-phenylalanine, was shown to be stable (no racemization and no hydrolysis) when the resolution and work-up processes were conducted within the pH range of 2-12 at temperatures below 25°C (higher temperatures were not studied). FPA meeting specification was isolated in yields of ca. 95% by simple acidification of its aqueous salt solutions and filtration. 

Carbon-carbon bond formation reactions with peroxides are quite limited, in view of the synthetic features. However, the following atom-transfer reaction may be useful. Treatment of iodomethyl phenyl sulfone (45) with benzoyl peroxide generates an electrophilic benzenesulfonylmethyl radical, which adds to electron-rich 1-hexene to give the addition product (46) (eq. 4.18) [49-51]. The same treatment of bromoacetic acid and 1-hexene with benzoyl peroxide affords 7-butyl-7-lactone through the cyclization of the formed 7-bromoctanoic acid. 

Sulfite was converted by acidification to bisulfite and determined as such by DIE (16). Advantage was taken of the heat of the classical adduct formation reaction with formaldehyde ... 

Diazasilines, l,2-dihydro-2,2-diphenyl-, formation, reaction with DMAD, 57, 24... 

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