Fluazifop-butyl

The piedominant use of P-picoline (3) is as a starting material for agrochemicals and pharmaceuticals. For example, it is used to make insecticides such as chlorpyrifos (43), food additives such as niacin (27) and its amide (26), and herbicides such as fluazifop-butyl [69806-50-4] (63). 

Aliphatic hydrocarbons, triazine, substituted urea type and phenoxyacetic acid types of herbicides, Fluazifop and Fluazifop-butyl herbicides, ethylene diamine tetracetic acid salts in soil, aliphatic and polyaromatic hydrocarbons, phthalate esters, various organosulphur compounds, triazine herbicides, optical whiteners, mixtures of organic compounds and organotin compounds in non-saline sediments, aromatic hydrocarbons, humic and fulvic acids and mixtures of organic compounds in saline sediments and non-ionic surfactants and cobalamin in sludges. 

Fluazifop-butyl (2-(4-5, trifluoromethyl 2-pyridyloxy)phenoxy)propionate) and Fluazifop... 

Higher alkyl esters are also cleaved, as shown here with the propyl ester propanidid and the butyl ester fluazifop-butyl. Propanidid (7.50) is a shortacting anesthetic agent whose duration of action is controlled by its rate of... 

Fluazifop-butyl (26) (78BEP865137) is a promising heterocyclic representative of a new group of phenoxypropionic acids that are not auxin mimics. 

Phenoxypropionic acid herbicides contain a stereogenic center that can be derived from 2-chloro-propionic acid and include fluazifop-butyl (29) and flamprop (30).245... 

Uses Fluazifop-p-butyl is a selective postemergence phenoxy herbicide. It is used for control of the annual and perennial grass weeds in cotton, soybeans, stone fruits, asparagus, coffee, and others. The formulation is an emulsifiable concentrate. Fluazifop-p-butyl formulations may contain some fluazifop-butyl.1317... 

Frumin AL disulfoton Fuji-one isoprothiolane Fuji-grass esprocarb Fuklasin ziram Fumazone DBCP Fundal chlordimeform Fungaflor imazalil Fungazil imazalil Furadan carbofuran Furore fenoxaprop-ethyl Fusarex tecnazene Fusilade fluazifop-butyl... 

DB dichlorprop diclofop-methyl fenoprop fenoxaprop-ethyl fluazifop-butyl haloxyfop-methyl MCPA... 

Ramsey, J.D., B.H. Woollen, T.R. Anton and R.C. Scott (1994). The predictive accuracy of in vitro measurements for the dermal absorption of a lipophilic penetrant (fluazifop-butyl) through rat and human skin. Fund. Appl. Toxicol, 23, 230-236. 

Zeneca market a herbicide for broad leaved crops, Fusilade28 (fluazifop butyl) 113. This is a carboxylic ester with two ether linkages, one between two aromatic rings. 

Fluazifop-butyl Technical Data Sheet, Zeneca Plant Protection, Fernhurst, 1981 D. W. Bewick, Eur. Pat., 133,033 (Chem. Abstr., 1985,102, 165,249). 

Fluazifop-butyl (28), formerly PP 009, is a patented herbicide of the Ishihara Sangyo Kaisha Ltd. (Plowman et al., 1980.), it s chemical name is butyl 2-[4-(trifluoromethyl-2-pyridyloxy)phenoxy] propionate. 

Fluazifop-butyl is a systemic herbicide, very active against annual and perennial grass weeds and selective to broad-leaved crops. It has been widely tested in about... 

Studies on the mode of action of fluazifop-butyl have shown that it moves in the xylem and the phloem, which may account for the fact that its effect does not depend on the growth stage of grasses. 

Fluazifop-butyl has a preemergence activity too, lasting about 3-6 weeks according to soil type. This activity is only 25-50% of the herbicidal effect of postemergence application. Its selectivity is believed to be due to rapid degradation followed by conjugate formation in broad-leaved plants (Plowman et ai, 1980). 

Results from acute and sub-acute toxicological studies indicate that fluazifop-butyl and its first metabolite (fluazifpp-acid) are of low order of toxicity. 

The acute oral ld, of fluazifop-butyl for rats is 2925 and for mice 1490 (male), and 1770 (female) mg/kg respectively. The 24-hour dermal for rats and rabbits are 5000 and 8000 mg/kg, respectively. 

Fluazifop-butyl is slightly irritant to rat and rabbit skin and is a weak sensitiser of guinea pig skin. 

Fluazifop-butyl is also of low toxicity to birds and invertebrates, the acute oral LDjo for mallard ducks is 17 000 mg/kg, the highest dose that could be administered. No effect was seen on bees when administered both orally and by contact at 240 ig active ingredient/bee and 120 figfbee, respectively. Earthworms were unaffected 1 and 6 months after application to field plants at 5 kg active ingredient/ha. The ECj for Daphnia magna was > 10 mg active ingredient/1 after 24 and 48 hours. Fluazifop-butyl is moderately toxic to fish. The lCj at 96 hours, for rainbow trout (Salmo gairdneri) is 1.6 ppm. 

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